| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T9 |
0-10 |
Sentence |
denotes |
Highlights |
| T10 |
11-68 |
Sentence |
denotes |
• COVID-19 has been associated with cardiac involvement. |
| T11 |
69-116 |
Sentence |
denotes |
SARS-CoV-2 requires binding to ACE2 in the RAS. |
| T12 |
117-231 |
Sentence |
denotes |
• The ACE2/Ang1-7/Mas pathway counterbalances the RAS, which results in activation of anti-inflammatory pathways. |
| T13 |
232-306 |
Sentence |
denotes |
• ACE inhibitors, ARBs, and MRAs upregulate ACE2 activity and expression. |
| T14 |
307-458 |
Sentence |
denotes |
• More data are required to determine if regulation of ACE2 in patients with cardiovascular disease and COVID-19 would help improve clinical outcomes. |
