LitCovid-sentences  

PMC:7160614 / 2591-5335 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T27 0-12 Sentence denotes Introduction
T28 13-211 Sentence denotes On January 30, 2020, the World Health Organization (WHO) has declared the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak as a global health emergency of international concern.
T29 212-306 Sentence denotes This outbreak has infected all provinces of China and rapidly spread to the rest of the world.
T30 307-430 Sentence denotes At the time of writing this article (March 16, 2020), there have been more than 158 countries and territories affected [1].
T31 431-759 Sentence denotes Whole-genome sequencing and phylogenetic analysis reveal that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is similar to some beta coronaviruses detected in bats, but it is distinct from severe acute respiratory syndrome coronavirus (SARS-Cov) and Middle East respiratory syndrome coronavirus (MERS-CoV) [2].
T32 760-888 Sentence denotes Patients with COVID-19 develop pneumonia with associated symptoms of fever (98%), cough (76%), and myalgia or fatigue (44%) [3].
T33 889-987 Sentence denotes CT imaging plays a critical role in the diagnosis and the monitoring of disease progression [4–6].
T34 988-1215 Sentence denotes The latest research studies described the characteristic imaging manifestations of COVID-19, including ground-glass opacities (GGO) (57 to 88%), bilateral involvement (76 to 88%), and peripheral distribution (33 to 85%) [7–10].
T35 1216-1352 Sentence denotes Other imaging features such as consolidation, cavitation, and interlobular septal thickening are also reported in some patients [11–13].
T36 1353-1473 Sentence denotes However, these imaging manifestations of COVID-19 are nonspecific and are difficult to distinguish from other pneumonia.
T37 1474-1630 Sentence denotes To our knowledge, there have been no studies explicitly comparing imaging and clinical characteristics between pneumonia patients with and without COVID-19.
T38 1631-1828 Sentence denotes The current diagnostic criterion for COVID-19 is the positive result of a nucleic acid test by real-time reverse transcription polymerase chain reaction (RT-PCR) or next-generation sequencing [14].
T39 1829-1996 Sentence denotes However, false-negative results caused by unstable specimen processing are relatively high in clinical practice, which has worsened the spread of the outbreak [15–18].
T40 1997-2111 Sentence denotes Moreover, laboratory testing for SARS-CoV-2 requires a rigorous platform, which is not assembled in all hospitals.
T41 2112-2186 Sentence denotes Thus, this requires specimen transfer, which may delay diagnosis for days.
T42 2187-2330 Sentence denotes Early and accurate diagnosis is crucial, particularly for critically ill patients who need emergency surgery, and with pneumonia complications.
T43 2331-2504 Sentence denotes To solve these problems, we hypothesize that a diagnostic model can be developed based on CT imaging and clinical manifestations alone, independent of the nucleic acid test.
T44 2505-2630 Sentence denotes In this study, we identify the differences in imaging and clinical manifestations between patients with and without COVID-19.
T45 2631-2744 Sentence denotes We also develop and validate a model for COVID-19 diagnosis based on radiological semantic and clinical features.