PMC:7160614 / 14278-20661 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T120 0-50 Sentence denotes Imaging and clinical manifestations between groups
T121 51-256 Sentence denotes The differences between patients with and without COVID-19 for all 67 features (41 imaging and 26 critical clinical features) are shown in Tables 1 and 2 and the Supplementary Materials (Tables E3 and E4).
T122 257-404 Sentence denotes The differences between the primary cohort and validation cohort for the same features are shown in the Supplementary Materials (Tables E5 and E6).
T123 405-562 Sentence denotes All characteristics except fatigue and white blood cell count in the CR model presented no significant difference between the primary and validation cohorts.
T124 563-674 Sentence denotes A total of 1745 lesions were identified, with 1062 from the COVID-19 group and 683 from the non-COVID-19 group.
T125 675-754 Sentence denotes Table 1 Radiological semantic features of patients in COVID-19 and non-COVID-19
T126 755-810 Sentence denotes Feature Non-COVID-19 (n = 66) COVID-19 (n = 70) p value
T127 811-829 Sentence denotes Number of pure GGO
T128 830-882 Sentence denotes   Total# 1.00 (0.00, 5.05) 3.50 (0.95, 8.05) 0.018b*
T129 883-945 Sentence denotes   Peripheral area# 1.00 (0.00, 4.05) 2.00 (0.00, 6.05) 0.032b*
T130 946-1033 Sentence denotes   Central/both peripheral and central area# 0.00 (0.00, 0.00) 0.00 (0.00, 2.00) 0.001b*
T131 1034-1053 Sentence denotes Number of mixed GGO
T132 1054-1106 Sentence denotes   Total# 1.00 (0.00, 3.05) 3.00 (1.00, 9.00) 0.001b*
T133 1107-1171 Sentence denotes   Peripheral area# 0.00 (0.00, 2.00) 2.50 (1.00, 6.00) < 0.001b*
T134 1172-1258 Sentence denotes   Central/both peripheral and central area# 0.00 (0.00, 1.05) 0.00 (0.00, 2.00) 0.657b
T135 1259-1288 Sentence denotes Total number of consolidation
T136 1289-1349 Sentence denotes   Consolidation# 1.00 (0.00, 3.00) 0.00 (0.00, 0.05) 0.001b*
T137 1350-1414 Sentence denotes   Pure solid nodules# 0.00 (0.00, 0.00) 0.00 (0.00, 0.00) 0.309b
T138 1415-1484 Sentence denotes   Solid nodules with GGO# 0.00 (0.00, 0.00) 0.00 (0.00, 1.00) 0.033b*
T139 1485-1508 Sentence denotes Total number of lesions
T140 1509-1571 Sentence denotes   Peripheral area# 5.00 (2.00, 9.05) 7.00 (2.00, 13.00) 0.112b
T141 1572-1630 Sentence denotes   Central area# 0.00 (0.00, 3.00) 0.00 (0.00, 1.05) 0.960b
T142 1631-1709 Sentence denotes   Both peripheral and central area# 0.00 (0.00, 2.00) 0.00 (0.00, 2.05) 0.582b
T143 1710-1748 Sentence denotes Interlobular septal thickening 0.009a*
T144 1749-1783 Sentence denotes   Negative 44 (66.67%) 31 (44.29%)
T145 1784-1818 Sentence denotes   Positive 22 (33.33%) 39 (55.71%)
T146 1819-1849 Sentence denotes Crazy paving pattern < 0.001a*
T147 1850-1884 Sentence denotes   Negative 60 (90.91%) 32 (45.71%)
T148 1885-1917 Sentence denotes   Positive 6 (9.09%) 38 (54.29%)
T149 1918-1944 Sentence denotes Tree-in-bud sign < 0.001a*
T150 1945-1979 Sentence denotes   Negative 37 (56.06%) 61 (87.14%)
T151 1980-2013 Sentence denotes   Positive 29 (43.94%) 9 (12.86%)
T152 2014-2040 Sentence denotes Pleural thickening 0.030a*
T153 2041-2075 Sentence denotes   Negative 46 (69.70%) 36 (51.43%)
T154 2076-2110 Sentence denotes   Positive 20 (30.30%) 34 (48.57%)
T155 2111-2161 Sentence denotes Offending vessel augmentation in lesions < 0.001a*
T156 2162-2196 Sentence denotes   Negative 55 (83.33%) 17 (24.29%)
T157 2197-2231 Sentence denotes   Positive 11 (16.67%) 53 (75.71%)
T158 2232-2258 Sentence denotes GGO ground-glass opacities
T159 2259-2402 Sentence denotes #Results are median with interquartile range in parentheses, and the remainder results are measurements with corresponding ratio in parentheses
T160 2403-2464 Sentence denotes *Data with statistical significance. pa: chi-square test, pb:
T161 2465-2481 Sentence denotes Student’s t test
T162 2482-2548 Sentence denotes Table 2 Clinical features of patients in COVID-19 and non-COVID-19
T163 2549-2604 Sentence denotes Feature Non-COVID-19 (n = 66) COVID-19 (n = 70) p value
T164 2605-2608 Sentence denotes Sex
T165 2609-2647 Sentence denotes   Male# 43 (65.15%) 41 (58.57%) 0.430a
T166 2648-2681 Sentence denotes   Female# 23 (34.85%) 29 (41.43%)
T167 2682-2730 Sentence denotes   Age (years) 46.73 ± 25.00 42.93 ± 13.32 0.275b
T168 2731-2742 Sentence denotes Vital signs
T169 2743-2812 Sentence denotes   Systolic blood pressure (mmHg) 126.92 ± 23.07 127.07 ± 15.16 0.965b
T170 2813-2881 Sentence denotes   Diastolic blood pressure (mmHg) 77.74 ± 15.72 80.39 ± 10.51 0.254b
T171 2882-2942 Sentence denotes   Respiration rate (bpm) 25.20 ± 7.29 19.86 ± 1.90 < 0.001b*
T172 2943-3000 Sentence denotes   Heart rate (bpm) 101.59 ± 20.36 86.06 ± 13.34 < 0.001b*
T173 3001-3053 Sentence denotes   Temperature (°C) 37.61 ± 1.06 37.12 ± 0.83 0.003b*
T174 3054-3059 Sentence denotes Signs
T175 3060-3104 Sentence denotes   Dry cough# 56 (84.85%) 48 (68.57%) 0.025a*
T176 3105-3146 Sentence denotes   Fatigue# 8 (12.12%) 22 (31.43%) 0.007a*
T177 3147-3189 Sentence denotes   Sore throat# 6 (9.09%) 9 (12.86%) 0.483a
T178 3190-3226 Sentence denotes   Stuffy# 4 (6.06%) 2 (2.86%) 0.623a
T179 3227-3267 Sentence denotes   Runny nose# 3 (4.55%) 3 (4.29%) 0.731a
T180 3268-3335 Sentence denotes White blood cell count (× 109/L) 11.48 ± 5.36 5.27 ± 2.33 < 0.001b*
T181 3336-3377 Sentence denotes White blood cell count category < 0.001c*
T182 3378-3404 Sentence denotes   Low# 0 (0.00%) 2 (2.86%)
T183 3405-3438 Sentence denotes   Normal# 27 (40.91%) 63 (90.00%)
T184 3439-3468 Sentence denotes   High# 39 (59.09%) 5 (7.14%)
T185 3469-3526 Sentence denotes Lymphocyte count (× 109/L) 1.57 ± 1.33 1.25 ± 0.68 0.086b
T186 3527-3562 Sentence denotes Lymphocyte count category < 0.001c*
T187 3563-3593 Sentence denotes   Low# 24 (36.36%) 32 (45.71%)
T188 3594-3627 Sentence denotes   Normal# 35 (53.03%) 37 (52.86%)
T189 3628-3656 Sentence denotes   High# 7 (10.61%) 1 (1.43%)
T190 3657-3717 Sentence denotes Neutrophil count (× 109/L) 8.97 ± 4.90 3.53 ± 2.17 < 0.001b*
T191 3718-3753 Sentence denotes Neutrophil count category < 0.001c*
T192 3754-3781 Sentence denotes   Low# 3 (4.55%) 8 (11.43%)
T193 3782-3815 Sentence denotes   Normal# 23 (34.85%) 59 (84.29%)
T194 3816-3845 Sentence denotes   High# 40 (60.61%) 3 (4.29%)
T195 3846-3909 Sentence denotes C-reactive protein (mg/L) 69.30 ± 65.88 26.37 ± 30.97 < 0.001b*
T196 3910-3963 Sentence denotes Procalcitonin (ng/mL) 3.36 ± 8.98 0.26 ± 0.84 0.007b*
T197 3964-4025 Sentence denotes *Data with statistical significance. pa: chi-square test, pb:
T198 4026-4047 Sentence denotes Student’s t test. pc:
T199 4048-4069 Sentence denotes Kruskal-Wallis H test
T200 4070-4135 Sentence denotes #Results are measurements with corresponding ratio in parentheses
T201 4136-4226 Sentence denotes For imaging manifestations, 7 patients in the COVID-19 group showed normal chest CT (10%).
T202 4227-4360 Sentence denotes COVID-19 patients have a greater number of pure GGO and mixed GGO than non-COVID-19 patients (p = 0.018 and p = 0.001, respectively).
T203 4361-4479 Sentence denotes For pure GGO lesions, the differences are significant both in peripheral (p = 0.032) and in central areas (p = 0.001).
T204 4480-4637 Sentence denotes However, the number of mixed GGO is mainly distributed at the periphery in COVID-19 patients (p < 0.001), with no statistical difference in the central area.
T205 4638-4723 Sentence denotes The consolidation lesions without GGO occurred less in COVID-19 patients (p = 0.001).
T206 4724-4865 Sentence denotes More lesions are between 1 and 3 cm (p = 0.027), and fewer lesions are larger than half of the lung segment (p = 0.017) in COVID-19 patients.
T207 4866-5224 Sentence denotes Other significant differences between the two groups include the pleural traction sign (p = 0.019), bronchial wall thickening (p < 0.001), interlobular septal thickening (p = 0.009), crazy paving (p < 0.001), tree-in-bud (p < 0.001), pleural effusions (p < 0.001), pleural thickening (p = 0.030), and the offending vessel augmentation in lesions (p < 0.001).
T208 5225-5320 Sentence denotes The lung score presents no significant difference between the COVID-19 and non-COVID-19 groups.
T209 5321-5437 Sentence denotes Comparison of clinical features between the two groups of patients with and without COVID-19 is reported in Table 2.
T210 5438-5511 Sentence denotes There is no significant difference in age and sex between the two groups.
T211 5512-5657 Sentence denotes Significant differences are found in common symptoms between groups, including fever (p = 0.003), dry cough (p = 0.025), and fatigue (p = 0.007).
T212 5658-5768 Sentence denotes The respiration rate and heart rate also show significant differences between the two groups (both p < 0.001).
T213 5769-5890 Sentence denotes Compared with non-COVID-19 pneumonia, the reduction of the WBC count is more pronounced in COVID-19 patients (p < 0.001).
T214 5891-6015 Sentence denotes The ratio of lymphocyte and ratio of neutrophil also show a significant difference between COVID-19 and non-COVID-19 groups.
T215 6016-6163 Sentence denotes Although lymphopenia was observed in 32 COVID-19 patients (45.71%), it is not statistically different compared with that in the non-COVID-19 group.
T216 6164-6315 Sentence denotes C-creative protein (CRP) level and procalcitonin level are also significantly different between the two groups (p < 0.001 and p = 0.007, respectively).
T217 6316-6383 Sentence denotes Most COVID-19 patients present normal procalcitonin level (82.86%).