Id |
Subject |
Object |
Predicate |
Lexical cue |
T120 |
0-50 |
Sentence |
denotes |
Imaging and clinical manifestations between groups |
T121 |
51-256 |
Sentence |
denotes |
The differences between patients with and without COVID-19 for all 67 features (41 imaging and 26 critical clinical features) are shown in Tables 1 and 2 and the Supplementary Materials (Tables E3 and E4). |
T122 |
257-404 |
Sentence |
denotes |
The differences between the primary cohort and validation cohort for the same features are shown in the Supplementary Materials (Tables E5 and E6). |
T123 |
405-562 |
Sentence |
denotes |
All characteristics except fatigue and white blood cell count in the CR model presented no significant difference between the primary and validation cohorts. |
T124 |
563-674 |
Sentence |
denotes |
A total of 1745 lesions were identified, with 1062 from the COVID-19 group and 683 from the non-COVID-19 group. |
T125 |
675-754 |
Sentence |
denotes |
Table 1 Radiological semantic features of patients in COVID-19 and non-COVID-19 |
T126 |
755-810 |
Sentence |
denotes |
Feature Non-COVID-19 (n = 66) COVID-19 (n = 70) p value |
T127 |
811-829 |
Sentence |
denotes |
Number of pure GGO |
T128 |
830-882 |
Sentence |
denotes |
Total# 1.00 (0.00, 5.05) 3.50 (0.95, 8.05) 0.018b* |
T129 |
883-945 |
Sentence |
denotes |
Peripheral area# 1.00 (0.00, 4.05) 2.00 (0.00, 6.05) 0.032b* |
T130 |
946-1033 |
Sentence |
denotes |
Central/both peripheral and central area# 0.00 (0.00, 0.00) 0.00 (0.00, 2.00) 0.001b* |
T131 |
1034-1053 |
Sentence |
denotes |
Number of mixed GGO |
T132 |
1054-1106 |
Sentence |
denotes |
Total# 1.00 (0.00, 3.05) 3.00 (1.00, 9.00) 0.001b* |
T133 |
1107-1171 |
Sentence |
denotes |
Peripheral area# 0.00 (0.00, 2.00) 2.50 (1.00, 6.00) < 0.001b* |
T134 |
1172-1258 |
Sentence |
denotes |
Central/both peripheral and central area# 0.00 (0.00, 1.05) 0.00 (0.00, 2.00) 0.657b |
T135 |
1259-1288 |
Sentence |
denotes |
Total number of consolidation |
T136 |
1289-1349 |
Sentence |
denotes |
Consolidation# 1.00 (0.00, 3.00) 0.00 (0.00, 0.05) 0.001b* |
T137 |
1350-1414 |
Sentence |
denotes |
Pure solid nodules# 0.00 (0.00, 0.00) 0.00 (0.00, 0.00) 0.309b |
T138 |
1415-1484 |
Sentence |
denotes |
Solid nodules with GGO# 0.00 (0.00, 0.00) 0.00 (0.00, 1.00) 0.033b* |
T139 |
1485-1508 |
Sentence |
denotes |
Total number of lesions |
T140 |
1509-1571 |
Sentence |
denotes |
Peripheral area# 5.00 (2.00, 9.05) 7.00 (2.00, 13.00) 0.112b |
T141 |
1572-1630 |
Sentence |
denotes |
Central area# 0.00 (0.00, 3.00) 0.00 (0.00, 1.05) 0.960b |
T142 |
1631-1709 |
Sentence |
denotes |
Both peripheral and central area# 0.00 (0.00, 2.00) 0.00 (0.00, 2.05) 0.582b |
T143 |
1710-1748 |
Sentence |
denotes |
Interlobular septal thickening 0.009a* |
T144 |
1749-1783 |
Sentence |
denotes |
Negative 44 (66.67%) 31 (44.29%) |
T145 |
1784-1818 |
Sentence |
denotes |
Positive 22 (33.33%) 39 (55.71%) |
T146 |
1819-1849 |
Sentence |
denotes |
Crazy paving pattern < 0.001a* |
T147 |
1850-1884 |
Sentence |
denotes |
Negative 60 (90.91%) 32 (45.71%) |
T148 |
1885-1917 |
Sentence |
denotes |
Positive 6 (9.09%) 38 (54.29%) |
T149 |
1918-1944 |
Sentence |
denotes |
Tree-in-bud sign < 0.001a* |
T150 |
1945-1979 |
Sentence |
denotes |
Negative 37 (56.06%) 61 (87.14%) |
T151 |
1980-2013 |
Sentence |
denotes |
Positive 29 (43.94%) 9 (12.86%) |
T152 |
2014-2040 |
Sentence |
denotes |
Pleural thickening 0.030a* |
T153 |
2041-2075 |
Sentence |
denotes |
Negative 46 (69.70%) 36 (51.43%) |
T154 |
2076-2110 |
Sentence |
denotes |
Positive 20 (30.30%) 34 (48.57%) |
T155 |
2111-2161 |
Sentence |
denotes |
Offending vessel augmentation in lesions < 0.001a* |
T156 |
2162-2196 |
Sentence |
denotes |
Negative 55 (83.33%) 17 (24.29%) |
T157 |
2197-2231 |
Sentence |
denotes |
Positive 11 (16.67%) 53 (75.71%) |
T158 |
2232-2258 |
Sentence |
denotes |
GGO ground-glass opacities |
T159 |
2259-2402 |
Sentence |
denotes |
#Results are median with interquartile range in parentheses, and the remainder results are measurements with corresponding ratio in parentheses |
T160 |
2403-2464 |
Sentence |
denotes |
*Data with statistical significance. pa: chi-square test, pb: |
T161 |
2465-2481 |
Sentence |
denotes |
Student’s t test |
T162 |
2482-2548 |
Sentence |
denotes |
Table 2 Clinical features of patients in COVID-19 and non-COVID-19 |
T163 |
2549-2604 |
Sentence |
denotes |
Feature Non-COVID-19 (n = 66) COVID-19 (n = 70) p value |
T164 |
2605-2608 |
Sentence |
denotes |
Sex |
T165 |
2609-2647 |
Sentence |
denotes |
Male# 43 (65.15%) 41 (58.57%) 0.430a |
T166 |
2648-2681 |
Sentence |
denotes |
Female# 23 (34.85%) 29 (41.43%) |
T167 |
2682-2730 |
Sentence |
denotes |
Age (years) 46.73 ± 25.00 42.93 ± 13.32 0.275b |
T168 |
2731-2742 |
Sentence |
denotes |
Vital signs |
T169 |
2743-2812 |
Sentence |
denotes |
Systolic blood pressure (mmHg) 126.92 ± 23.07 127.07 ± 15.16 0.965b |
T170 |
2813-2881 |
Sentence |
denotes |
Diastolic blood pressure (mmHg) 77.74 ± 15.72 80.39 ± 10.51 0.254b |
T171 |
2882-2942 |
Sentence |
denotes |
Respiration rate (bpm) 25.20 ± 7.29 19.86 ± 1.90 < 0.001b* |
T172 |
2943-3000 |
Sentence |
denotes |
Heart rate (bpm) 101.59 ± 20.36 86.06 ± 13.34 < 0.001b* |
T173 |
3001-3053 |
Sentence |
denotes |
Temperature (°C) 37.61 ± 1.06 37.12 ± 0.83 0.003b* |
T174 |
3054-3059 |
Sentence |
denotes |
Signs |
T175 |
3060-3104 |
Sentence |
denotes |
Dry cough# 56 (84.85%) 48 (68.57%) 0.025a* |
T176 |
3105-3146 |
Sentence |
denotes |
Fatigue# 8 (12.12%) 22 (31.43%) 0.007a* |
T177 |
3147-3189 |
Sentence |
denotes |
Sore throat# 6 (9.09%) 9 (12.86%) 0.483a |
T178 |
3190-3226 |
Sentence |
denotes |
Stuffy# 4 (6.06%) 2 (2.86%) 0.623a |
T179 |
3227-3267 |
Sentence |
denotes |
Runny nose# 3 (4.55%) 3 (4.29%) 0.731a |
T180 |
3268-3335 |
Sentence |
denotes |
White blood cell count (× 109/L) 11.48 ± 5.36 5.27 ± 2.33 < 0.001b* |
T181 |
3336-3377 |
Sentence |
denotes |
White blood cell count category < 0.001c* |
T182 |
3378-3404 |
Sentence |
denotes |
Low# 0 (0.00%) 2 (2.86%) |
T183 |
3405-3438 |
Sentence |
denotes |
Normal# 27 (40.91%) 63 (90.00%) |
T184 |
3439-3468 |
Sentence |
denotes |
High# 39 (59.09%) 5 (7.14%) |
T185 |
3469-3526 |
Sentence |
denotes |
Lymphocyte count (× 109/L) 1.57 ± 1.33 1.25 ± 0.68 0.086b |
T186 |
3527-3562 |
Sentence |
denotes |
Lymphocyte count category < 0.001c* |
T187 |
3563-3593 |
Sentence |
denotes |
Low# 24 (36.36%) 32 (45.71%) |
T188 |
3594-3627 |
Sentence |
denotes |
Normal# 35 (53.03%) 37 (52.86%) |
T189 |
3628-3656 |
Sentence |
denotes |
High# 7 (10.61%) 1 (1.43%) |
T190 |
3657-3717 |
Sentence |
denotes |
Neutrophil count (× 109/L) 8.97 ± 4.90 3.53 ± 2.17 < 0.001b* |
T191 |
3718-3753 |
Sentence |
denotes |
Neutrophil count category < 0.001c* |
T192 |
3754-3781 |
Sentence |
denotes |
Low# 3 (4.55%) 8 (11.43%) |
T193 |
3782-3815 |
Sentence |
denotes |
Normal# 23 (34.85%) 59 (84.29%) |
T194 |
3816-3845 |
Sentence |
denotes |
High# 40 (60.61%) 3 (4.29%) |
T195 |
3846-3909 |
Sentence |
denotes |
C-reactive protein (mg/L) 69.30 ± 65.88 26.37 ± 30.97 < 0.001b* |
T196 |
3910-3963 |
Sentence |
denotes |
Procalcitonin (ng/mL) 3.36 ± 8.98 0.26 ± 0.84 0.007b* |
T197 |
3964-4025 |
Sentence |
denotes |
*Data with statistical significance. pa: chi-square test, pb: |
T198 |
4026-4047 |
Sentence |
denotes |
Student’s t test. pc: |
T199 |
4048-4069 |
Sentence |
denotes |
Kruskal-Wallis H test |
T200 |
4070-4135 |
Sentence |
denotes |
#Results are measurements with corresponding ratio in parentheses |
T201 |
4136-4226 |
Sentence |
denotes |
For imaging manifestations, 7 patients in the COVID-19 group showed normal chest CT (10%). |
T202 |
4227-4360 |
Sentence |
denotes |
COVID-19 patients have a greater number of pure GGO and mixed GGO than non-COVID-19 patients (p = 0.018 and p = 0.001, respectively). |
T203 |
4361-4479 |
Sentence |
denotes |
For pure GGO lesions, the differences are significant both in peripheral (p = 0.032) and in central areas (p = 0.001). |
T204 |
4480-4637 |
Sentence |
denotes |
However, the number of mixed GGO is mainly distributed at the periphery in COVID-19 patients (p < 0.001), with no statistical difference in the central area. |
T205 |
4638-4723 |
Sentence |
denotes |
The consolidation lesions without GGO occurred less in COVID-19 patients (p = 0.001). |
T206 |
4724-4865 |
Sentence |
denotes |
More lesions are between 1 and 3 cm (p = 0.027), and fewer lesions are larger than half of the lung segment (p = 0.017) in COVID-19 patients. |
T207 |
4866-5224 |
Sentence |
denotes |
Other significant differences between the two groups include the pleural traction sign (p = 0.019), bronchial wall thickening (p < 0.001), interlobular septal thickening (p = 0.009), crazy paving (p < 0.001), tree-in-bud (p < 0.001), pleural effusions (p < 0.001), pleural thickening (p = 0.030), and the offending vessel augmentation in lesions (p < 0.001). |
T208 |
5225-5320 |
Sentence |
denotes |
The lung score presents no significant difference between the COVID-19 and non-COVID-19 groups. |
T209 |
5321-5437 |
Sentence |
denotes |
Comparison of clinical features between the two groups of patients with and without COVID-19 is reported in Table 2. |
T210 |
5438-5511 |
Sentence |
denotes |
There is no significant difference in age and sex between the two groups. |
T211 |
5512-5657 |
Sentence |
denotes |
Significant differences are found in common symptoms between groups, including fever (p = 0.003), dry cough (p = 0.025), and fatigue (p = 0.007). |
T212 |
5658-5768 |
Sentence |
denotes |
The respiration rate and heart rate also show significant differences between the two groups (both p < 0.001). |
T213 |
5769-5890 |
Sentence |
denotes |
Compared with non-COVID-19 pneumonia, the reduction of the WBC count is more pronounced in COVID-19 patients (p < 0.001). |
T214 |
5891-6015 |
Sentence |
denotes |
The ratio of lymphocyte and ratio of neutrophil also show a significant difference between COVID-19 and non-COVID-19 groups. |
T215 |
6016-6163 |
Sentence |
denotes |
Although lymphopenia was observed in 32 COVID-19 patients (45.71%), it is not statistically different compared with that in the non-COVID-19 group. |
T216 |
6164-6315 |
Sentence |
denotes |
C-creative protein (CRP) level and procalcitonin level are also significantly different between the two groups (p < 0.001 and p = 0.007, respectively). |
T217 |
6316-6383 |
Sentence |
denotes |
Most COVID-19 patients present normal procalcitonin level (82.86%). |