PMC:7160441 / 6599-9811 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T69 0-10 Sentence denotes Discussion
T70 11-249 Sentence denotes This is the first time that an increase in ILI cases was observed simultaneously in several regions after the peak of the annual influenza epidemic in the last 30 seasons of routine surveillance in France with the Sentinelles network [9].
T71 250-441 Sentence denotes Several processes may have contributed to this observation, including, among others, characteristics of the influenza season, change in population behaviour or increase in COVID-19 incidence.
T72 442-547 Sentence denotes Influenza A (H1N1)pdm09 and influenza B viruses co-circulated in 2019/20 in France [10] (see Supplement).
T73 548-663 Sentence denotes Seasons with type B virus circulation can lead to a slow decay in incidence but a renewed increase is atypical [1].
T74 664-772 Sentence denotes The 2-week-long normal school holidays started between mid-February and early March depending on the region.
T75 773-925 Sentence denotes While holidays may change the dynamics of influenza [9], this generally has an effect in the ascending phase of the epidemic rather than after the peak.
T76 926-1108 Sentence denotes The COVID-19 pandemic may have changed the health-seeking behaviour of patients and, to some extent, the reporting of the contributing GPs although they conform to a case definition.
T77 1109-1218 Sentence denotes In the crowdsourced surveillance system grippenet.fr [10], there was no evidence of increasing consultations:
T78 1219-1298 Sentence denotes 30% consulted with a GP in for ILI during week 10, compared with 38% in week 9.
T79 1299-1470 Sentence denotes As information regarding the coronavirus risk is widespread, a uniform increase in all regions could have been expected in this scenario rather than only in a few regions.
T80 1471-1591 Sentence denotes We however acknowledge that increased consultation rates in regions where COVID-19 is the most reported may be possible.
T81 1592-1718 Sentence denotes The similarity between COVID-19 and influenza symptoms makes it possible that the excess ILI cases were due to COVID-19 cases.
T82 1719-1803 Sentence denotes The presence of SARS-CoV-2-positive swabs in the patients supports this possibility.
T83 1804-1920 Sentence denotes The correlation between the number of confirmed cases and the computed excess is also consistent with this scenario.
T84 1921-2036 Sentence denotes In this case, the excess in cases is compatible with an exponential growth at an estimated rate of ca 0.7 per week.
T85 2037-2138 Sentence denotes Interestingly, this estimate was very similar in the four most affected regions (GRE, IDF, OCC, HDF).
T86 2139-2233 Sentence denotes It may prove useful to help calibrate models for studying the impact of the COVID-19 pandemic.
T87 2234-2388 Sentence denotes Estimating the true number of COVID-19 cases can only be tentative at this early stage of the epidemic with data from a non-dedicated surveillance system.
T88 2389-2480 Sentence denotes It is likely that the case definition of ILI does not allow identifying all COVID-19 cases.
T89 2481-2574 Sentence denotes In addition, only a few cases were virologically tested, adding uncertainty in the estimates.
T90 2575-2783 Sentence denotes Yet, the rate of excess ILI consultations applied to the French regions yielded a number of cases far in excess of confirmed cases, with 12,840 cases in IDF and around 10,000 cases in the regions GRE and HDF.
T91 2784-3037 Sentence denotes Likewise, the extrapolated number of COVID-19 presenting as ARI was 760 in those older than 65 years in the two eastern regions (GRE and BFC): this was already twice the number of reported cases in these regions at the time (n = 379), all ages combined.
T92 3038-3212 Sentence denotes As we enter a period of generalised circulation of SARS-CoV-2, surveillance based on clinical description and swabbing by GPs will prove essential in assessing the situation.