PMC:7156903 / 19602-23900 JSONTXT 13 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T147 0-27 Sentence denotes Role of imaging in COVID-19
T148 28-236 Sentence denotes On the frontlines of fighting the COVID-19 epidemic, chest imaging (particularly chest CT) now has an irreplaceable role in the early diagnosis of COVID-19 as well as monitoring the disease’s clinical course.
T149 237-384 Sentence denotes COVID-19 has characteristic manifestations in the lung that are readily detected on chest CT as described in some recent publications [15, 24, 25].
T150 385-579 Sentence denotes In several prior reports, chest CT showed progression of disease that corresponded with worsening clinical symptoms and also disease resolution as the patients clinically recovered [21, 22, 27].
T151 580-759 Sentence denotes In a recent report [20], the predominant pattern of abnormality in COVID-19 observed on the basis of the interval between symptom onset and the first CT scan has some differences.
T152 760-1032 Sentence denotes Lesions quickly evolved from focal unilateral to diffuse bilateral ground glass opacities that progressed to or co-existed with consolidations within 1–3 weeks, indicating the change through clinical course which was also reflected on the number of involved lung segments.
T153 1033-1340 Sentence denotes In a prior study of 51 patients, the absolute number of lung findings increased with the time from symptom onset and lesions with consolidations including ground glass opacities with consolidation and pure consolidation showed mildly positive correlation with the time between symptom onset and the CT [25].
T154 1341-1496 Sentence denotes Another report demonstrated mild or moderate progression of disease as manifested by increasing extent and density of lung opacities during follow-up [24].
T155 1497-1703 Sentence denotes In the context of typical clinical presentation and exposure history, some patients may present with negative results of RT-PCR for COVID-19 but have characteristic imaging features of COVID-19 on chest CT.
T156 1704-1828 Sentence denotes Subsequently, these patients whose labs were initially negative for COVID-19 did test positive later with repeat swab tests.
T157 1829-1995 Sentence denotes Thus, in patients at high risk for COVID-19, chest CT evidence of viral pneumonia may precede negative RT-PCR test results and present as an important warning signal.
T158 1996-2160 Sentence denotes A combination of repeated swab tests and CT scanning may be helpful for individuals with high clinical suspicion of COVID-19 but negative RT-PCR screening [28, 29].
T159 2161-2219 Sentence denotes Chest CT has a high sensitivity for diagnosis of COVID-19.
T160 2220-2451 Sentence denotes In a report of 51 patients with chest CT and RT-PCR assay performed within 3 days, the sensitivity of chest CT was greater than that of RT-PCR for COVID-19 at initial patient presentation (98% vs 71%, respectively, p < 0.001) [30].
T161 2452-2556 Sentence denotes In another study of 1014 patients, 59% had positive RT-PCR results, and 88% had positive chest CT scans.
T162 2557-2649 Sentence denotes The sensitivity of chest CT in suggesting COVID-19 was 97% based on positive RT-PCR results.
T163 2650-2792 Sentence denotes Between 60% and 93% of cases had initial positive CT consistent with COVID-19 prior (or parallel) to the initial positive RT-PCR results [31].
T164 2793-2845 Sentence denotes In addition, chest CT can evaluate disease severity.
T165 2846-3035 Sentence denotes In terms of the percentage of pneumonia lesions in the entire lung volume, the difference between the earlier stage patients and the severe stage patients is statistically significant [32].
T166 3036-3301 Sentence denotes In an initial prospective analysis of the clinical features of 41 patients, chest CT images of ICU patients on admission showed bilateral multiple lobular and subsegmental areas of consolidation, and overall had more imaging abnormalities than non-ICU patients [1].
T167 3302-3430 Sentence denotes Older patients may have more systemic symptoms, more extensive lung involvement, and worse prognosis than younger patients [33].
T168 3431-3642 Sentence denotes Thus, the typical CT findings of COVID-19 can not only help early screening suspected cases, but can also monitor the clinical progression and may predict severe complications such as acute respiratory diseases.
T169 3643-3803 Sentence denotes With high sensitivity for COVID-19, chest CT would play a very important role in the diagnosis and treatment of COVID-19 in the high-risk regions and countries.
T170 3804-3983 Sentence denotes In some extreme situations in very high-risk areas (Wuhan, China), CT was the one of main diagnostic criteria for this disease due to the relatively high false negative of RT-PCR.
T171 3984-4105 Sentence denotes For some low-risk regions and countries, positive predictive value of CT alone or adding CT to RT-PCR should be adjusted.
T172 4106-4161 Sentence denotes The proposition of CT could be tempered to some degree.
T173 4162-4298 Sentence denotes Therefore, to be more accurate, the role of chest CT in COVID-19 should be assessed based on the prevalence of the disease in each area.