PMC:7153689 / 3225-5182 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T23 0-39 Sentence denotes Halting the Spread with Rapid Diagnosis
T24 40-123 Sentence denotes A critical factor in slowing down the pandemic is the rapid diagnosis of new cases.
T25 124-327 Sentence denotes Nucleic acid amplification tests, such as real-time reverse transcription polymerase chain reaction (RT-PCR), provide the earliest and most accurate diagnosis, but they are costly and time consuming (7).
T26 328-541 Sentence denotes Point-of-care tests, e.g. lateral flow assays for the detection of antibodies are more ideal in the field; however, these tests are of limited value due accuracy issues and the time required to obtain a diagnosis.
T27 542-644 Sentence denotes Rapid antigen detection tests are still undergoing evaluation, and their efficacy is yet to be proven.
T28 645-786 Sentence denotes Figure 3 illustrates various tests being evaluated for COVID-19 and their diagnostic coverage from the acute phase to the convalescent phase.
T29 787-862 Sentence denotes The sources and accessibility of specimens are also critical for diagnosis.
T30 863-1017 Sentence denotes For upper respiratory specimens, the viral Ribonucleic acid yield from nasopharyngeal swabs seems to offer more accurate results than oropharyngeal swabs.
T31 1018-1188 Sentence denotes The SARS-CoV-2 virus is also detectable in blood, urine and stool; such specimens are not as reliable for diagnosis but are important from the transmission point of view.
T32 1189-1334 Sentence denotes Proper transport and handling of specimens is necessary to ensure the integrity of the viral RNA and, hence, the accuracy of the diagnostic test.
T33 1335-1560 Sentence denotes Adherence to biosafety practices is essential, and any testing should be performed in appropriately equipped laboratories by staff trained in the relevant technical and safety procedures (World Health Organization, 2020) (8).
T34 1561-1818 Sentence denotes Non-propagative diagnostic laboratory work should be conducted at a biosafety level 2 (BSL-2) facility, whereas propagative work, including virus culture and isolation, should be conducted at a containment laboratory with inward directional airflow (BSL-3).
T35 1819-1957 Sentence denotes Virus isolation is not routine but necessary for characterisation and to support the development of vaccines and other therapeutic agents.