PMC:7152911 / 70722-72704 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T578 0-47 Sentence denotes 2.2.6 Cell- and molecularly-imprinted polymers
T579 48-440 Sentence denotes Given traditional biorecognition elements used in biosensing exhibit stability concerns, such as antibodies or aptamers, as discussed in Sections 2.2.1–2.2.4, there have been efforts to create engineered molecular biorecognition elements, such as scFvs. In contrast, materials-based biorecognition elements exploit the principle of target-specific morphology for selective capture (Pan et al.
T580 441-458 Sentence denotes 2018; Zhou et al.
T581 459-465 Sentence denotes 2019).
T582 466-619 Sentence denotes The most common approach in materials-based biorecognition is based on cell- and molecularly-imprinted polymers (CIPs and MIPs, respectively) (Gui et al.
T583 620-626 Sentence denotes 2018).
T584 627-782 Sentence denotes CIPs and MIPs have been created using various processes, including bacteria-mediated lithography, micro-contact stamping, and colloid imprints (Chen et al.
T585 783-800 Sentence denotes 2016a; Pan et al.
T586 801-807 Sentence denotes 2018).
T587 808-1030 Sentence denotes As shown in Fig. 3b, Jafari et al. used imprinted organosilica sol-gel films of tetraethoxysilane and (3-mercaptopropyl)trimethoxysilane (MPTS) for selective detection of E. coli using an impedimetric method (Jafari et al.
T588 1031-1037 Sentence denotes 2019).
T589 1038-1191 Sentence denotes Similarly, Golabi et al. used imprinted poly(3-aminophenylboronic acid) films for detection of Staphylococcus epidermidis (S. epidermidis) (Golabi et al.
T590 1192-1198 Sentence denotes 2017).
T591 1199-1405 Sentence denotes Despite the absence of a highly selective molecular biorecognition element, CIPs and MIPs exhibit selectivity when exposed to samples that contain multiple analytes (i.e., non-target species) (Golabi et al.
T592 1406-1425 Sentence denotes 2017; Jafari et al.
T593 1426-1441 Sentence denotes 2019; Qi et al.
T594 1442-1448 Sentence denotes 2013).
T595 1449-1539 Sentence denotes MIPs and CIPs are also of interest with regard to opportunities in biosensor regeneration.
T596 1540-1723 Sentence denotes Common adverse effects of regeneration on biosensors that employ molecular biorecognition elements, such as irreversible changes in structure, are less likely to affect MIPs and CIPs.
T597 1724-1923 Sentence denotes However, it is generally accepted that current CIPs and MIPs exhibit lower selectivity to target species than antibodies and aptamers due to reduction of available chemical selectivity (Cheong et al.
T598 1924-1975 Sentence denotes 2013; Kryscio and Peppas, 2012; Yáñez-Sedeño et al.
T599 1976-1982 Sentence denotes 2017).