PMC:7148425 / 967-2529 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T8 0-210 Sentence denotes The newly-emerged Coronavirus SARS-CoV-2 is highly infectious and has rapidly spread throughout the world with a case fatality rate (CFR) highly dependent on age and pre-existing conditions associated with age.
T9 211-487 Sentence denotes As more data become available, average CFRs in children appear negligible, in young adults perhaps up to 1%, but in people over 60 rising to 4%, over 70 up to 9% and over 80 even up to 18% (see, for example, https://www.cebm.net/covid-19/global-covid-19-case-fatality-rates/).
T10 488-771 Sentence denotes Clearly, these figures can vary tremendously from country to country, and depend on the state of health of the patients and the state of the health care system, but it is likely that this sort of age stratification reflects the general characteristics of Coronavirus disease (COVID).
T11 772-891 Sentence denotes Obviously, there is vigorous debate as to why this may be, but a common denominator is the waning of immunity with age.
T12 892-1134 Sentence denotes Although much effort is currently directed at repurposing licensed drugs as anti-virals, particularly those with anti-inflammatory effects [1] this is usually viewed as a stop-gap measure and hopes are pinned on developing effective vaccines.
T13 1135-1280 Sentence denotes An unprecedented world-wide effort is channelling academic and industrial resources into the rapid production and testing of SARS-CoV-2 vaccines.
T14 1281-1562 Sentence denotes Quite apart from the potential dangers of accelerated vaccine development [2], and remembering the additional danger of immune enhancement [3], even were this successful the question remains whether the most susceptible members of the population (say, those over 60) would benefit.