Id |
Subject |
Object |
Predicate |
Lexical cue |
T222 |
0-212 |
Sentence |
denotes |
Activities of healthcare providers and researchers during an infectious disease outbreak, including clinical trials, are aimed towards finding rapid and effective responses for the treatment of infected patients. |
T223 |
213-278 |
Sentence |
denotes |
These actions need to occur under appropriate ethical guidelines. |
T224 |
279-483 |
Sentence |
denotes |
The World Health Organization has guidelines that embed ethical approaches and considerations within the integrated global alert and response system for epidemics and other public health emergencies [51]. |
T225 |
484-681 |
Sentence |
denotes |
These are all applicable to cell-based clinical investigations and include assurance that these are scientifically valid and that potential risks are reasonable in relation to anticipated benefits. |
T226 |
682-892 |
Sentence |
denotes |
With respect to safety of MSC administration in critically ill patients, including those with ARDS resulting from other aetiologies, no significant issues have been described in published articles to date [51]. |
T227 |
893-1063 |
Sentence |
denotes |
With respect to efficacy, there is equipoise at present, as only one as yet unpublished exploratory trial of MSC administration has demonstrated beneficial outcomes [52]. |