PMC:7144273 / 2549-3738 JSONTXT 15 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T20 0-265 Sentence denotes For COVID-19 patients who develop ARDS requiring intubation and mechanical ventilation, shock and multiple organ failure can also develop, although whether this is a direct consequence of viral infection or due to complications of critical illness is not yet clear.
T21 266-382 Sentence denotes Current therapeutic approaches include aggressive standard supportive care and treatment of any other co-infections.
T22 383-579 Sentence denotes Antiviral medications, including remdesivir, lopinavir–ritonavir, or lopinavir–ritonavir and interferon (IFN)-β1, are under investigation but safety and potential efficacy remain to be determined.
T23 580-816 Sentence denotes Remdesivir and IFN-β1β appear to have superior antiviral activity to lopinavir and remdesivir in vitro for the Middle East respiratory syndrome (MERS) coronavirus but whether this is the case for SARS-CoV-2 remains to be determined [2].
T24 817-970 Sentence denotes The US Food and Drug Administration (FDA) has recently approved use of hydroxychloroquine in COVID-19 patients but the efficacy remains to be determined.
T25 971-1189 Sentence denotes Growing information also suggests that virus-induced cytokine storm in the lungs may drive severe pathogenesis and provide potential therapeutic targets, for example anti-interleukin (IL)-6 or anti-IL-1 approaches [3].