| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T70 |
0-88 |
Sentence |
denotes |
Integrating resistive metal tracks onto a COC substrate have also been done in the past. |
| T71 |
89-308 |
Sentence |
denotes |
Some papers describe the use of a surface modification step done before metal deposition in order to enhance adhesion between the COC and the metal layer, like a pretreatment with plasma [46] or an organic solvent [47]. |
| T72 |
309-391 |
Sentence |
denotes |
Other papers describe the direct deposition of metal onto the COC surface [28,48]. |
| T73 |
392-491 |
Sentence |
denotes |
Chung et al. specifically, fabricated an amplification chip in COC with integrated Au heaters [28]. |
| T74 |
492-622 |
Sentence |
denotes |
However, their system required heating from both sides as the used grade of COC has a glass transition temperature (Tg) of 130 °C. |
| T75 |
623-726 |
Sentence |
denotes |
This COC could not withstand the required heater temperatures to have enough heat flux into the system. |
| T76 |
727-861 |
Sentence |
denotes |
They had to heat up the heater to temperatures above 130 °C, which caused cracking of the heater tracks due to deformation of the COC. |
| T77 |
862-966 |
Sentence |
denotes |
With their double-sided heating they ensured that the reaction mixture had the desired PCR temperatures. |
| T78 |
967-1121 |
Sentence |
denotes |
However, double-sided heating doubles the amount of metal required, increases the amount of fabrication steps, and therefore increases the price per chip. |
