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PMC:7143583 JSONTXT 18 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 0-65 Sentence denotes A novel presentation of COVID-19 via community acquired infection
T2 67-80 Sentence denotes 1 Discussion
T3 81-157 Sentence denotes COVID-19 is a novel coronavirus first detected in Wuhan, China in late 2019.
T4 158-235 Sentence denotes Shortly after, it was detected in the United States by mid-January 20201 , 3.
T5 236-402 Sentence denotes The virus can cause severe respiratory tract infections in its host more often in the elderly, immunocompromised, or individuals with multiple medical comorbidities3.
T6 403-654 Sentence denotes Current data suggests that while up to 80% of those infected are either asymptomatic or experience mild symptoms, 15% of those infected will have severe disease requiring hospitalization, and 5% will require intensive care and mechanical ventilation2.
T7 655-832 Sentence denotes Typical symptoms include fever (88.7%), dry cough (67.8%), and fatigue, with symptoms such as sputum production, sore throat, headache, and GI symptoms occurring less commonly2.
T8 834-859 Sentence denotes 2 Visual case discussion
T9 860-950 Sentence denotes A 76 year old male patient presented with his wife for altered mental status and lethargy.
T10 951-1045 Sentence denotes The patient's wife stated that for the last three days the patient ``had not seemed himself''.
T11 1046-1109 Sentence denotes She described some confusion at home and decreased interaction.
T12 1110-1225 Sentence denotes She reported the patient had not had fevers at home or dry cough, however she had recently experienced a dry cough.
T13 1226-1311 Sentence denotes The couple spent the previous weekend at a nearby casino after taking public transit.
T14 1312-1453 Sentence denotes The patient and wife had no recent long distance of international travel and no known sick contacts or known exposure to COVID-19 + patients.
T15 1454-1508 Sentence denotes The patient had no known history of pulmonary disease.
T16 1509-1610 Sentence denotes When vital signs were obtained the patient was found to have an oxygen saturation of 70% on room air.
T17 1611-1754 Sentence denotes The patient was tachypneic to a rate of 23 but did not appear to be in respiratory distress and was able to answer questions in full sentences.
T18 1755-1790 Sentence denotes Lung sounds were clear bilaterally.
T19 1791-1884 Sentence denotes The patient was moved to an isolation room and was placed on 15 L O2 via non-rebreather mask.
T20 1885-1984 Sentence denotes The patient was then weaned and able to maintain oxygen saturation of 93% on 5 L via nasal cannula.
T21 1985-2040 Sentence denotes Cell counts and electrolytes were within normal limits.
T22 2041-2121 Sentence denotes The patient was negative for Flu A/B and had a negative respiratory viral panel.
T23 2122-2199 Sentence denotes Chest X-ray obtained showed nonspecific bibasilar airspace disease (Fig. 1 ).
T24 2200-2314 Sentence denotes Of note, the patient's D-dimer was elevated to 2574 and CT imaging was ordered to evaluate for pulmonary embolism.
T25 2315-2378 Sentence denotes CTA of the chest with PE protocol revealed bibasilar opacities.
T26 2379-2479 Sentence denotes The patient was admitted to the progressive care unit for respiratory support and COVID-19 rule out.
T27 2480-2514 Sentence denotes Fig. 1 Chest Radiograph (AP view):
T28 2515-2548 Sentence denotes Upper lung emphysematous changes.
T29 2549-2691 Sentence denotes Nonspecific bibasal airspace disease which could represent atypical infection or pulmonary edema superimposed on chronic inflammatory changes.
T30 2692-2734 Sentence denotes Stable mediastinal contour and heart size.
T31 2735-2769 Sentence denotes No large effusion or pneumothorax.
T32 2770-2874 Sentence denotes On follow-up, patient tested positive for COVID-19 with declining respiratory status over the next 24 h.
T33 2875-2975 Sentence denotes He was upgraded to the intensive care unit for high flow nasal cannula at 25 L/min with FiO2 of 0.6.
T34 2977-2986 Sentence denotes Questions
T35 2987-3017 Sentence denotes 1 What is the R° for COVID-19?
T36 3018-3100 Sentence denotes How does this compare to the R° for typical influenza?a 0.5, less than typical flu
T37 3101-3131 Sentence denotes b 1.3, the same as typical flu
T38 3132-3167 Sentence denotes c 1.5–1.8, the same as pandemic flu
T39 3168-3199 Sentence denotes d 2.2, higher than pandemic flu
T40 3200-3232 Sentence denotes e 3.0, the same as pandemic SARS
T41 3233-3309 Sentence denotes 2 What lab abnormalities can be expected in COVID-19+ patients?a Lymphopenia
T42 3310-3335 Sentence denotes b Elevated pro-calcitonin
T43 3336-3354 Sentence denotes c Elevated D-dimer
T44 3355-3364 Sentence denotes d A and B
T45 3365-3374 Sentence denotes e A and C
T46 3375-3384 Sentence denotes f B and C
T47 3385-3403 Sentence denotes g All of the above
T48 3405-3412 Sentence denotes Answers
T49 3413-3448 Sentence denotes 1 Correct Answer = D, Explanation:
T50 3449-3565 Sentence denotes The R0 is the expected number of secondary cases produced by a single typical infection in a susceptible population.
T51 3566-3757 Sentence denotes Based on the most up-to-date statistics, COVID-19 is considered highly virulent with an expected R0 of at least 2.2 much higher than the R0 of seasonal flu, which is typically closer to 1.3.1
T52 3758-3793 Sentence denotes 2 Correct Answer = E, Explanation:
T53 3794-3869 Sentence denotes Patient typically present with lymphopenia and mildly elevated AST and ALT.
T54 3870-3894 Sentence denotes Procalcitonin is normal.
T55 3895-4007 Sentence denotes Patient who present with severe lymphopenia and elevated D-dimer has an associated increased risk of mortality.1
T56 4009-4042 Sentence denotes Declaration of Competing Interest
T57 4043-4047 Sentence denotes None