| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T113 |
0-164 |
Sentence |
denotes |
The amino acid sequence of the planar interfacial surface located at the tip of the NTD was analysed for the presence of consensus ganglioside-binding domains [20]. |
| T114 |
165-272 |
Sentence |
denotes |
These motifs are constituted by a triad of mandatory amino acid residues such as (K,R)-Xn-(F,Y,W)-Xn-(K,R). |
| T115 |
273-402 |
Sentence |
denotes |
The Xn intercalating segments, usually four to five residues, may contain any amino acid, but often Gly, Pro and/or Ser residues. |
| T116 |
403-542 |
Sentence |
denotes |
The strict application of this algorithm did not allow the detection of any potential ganglioside-binding domain in this region of the NTD. |
| T117 |
543-650 |
Sentence |
denotes |
However, an intriguing over-representation of aromatic and basic residues was found in the 129–158 segment: |
| T118 |
651-690 |
Sentence |
denotes |
129-KVCEFQFCNDPFLGVYYHKNNKSWMESEFR-158. |
| T119 |
691-812 |
Sentence |
denotes |
This 30-amino acid stretch also contains Gly, Pro and/or Ser residues that are often found in ganglioside-binding motifs. |
| T120 |
813-932 |
Sentence |
denotes |
These observations supported the notion that the tip of the NTD could display a large ganglioside-attachment interface. |
