LitCovid-sentences  

PMC:7127386 / 8389-10625 JSONTXT 12 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T47 0-47 Sentence denotes Compounds Inhibition of SARS-CoV-2 in vitro, μM
T48 48-93 Sentence denotes Name Bioactivity Clinical application CAS No.
T49 94-193 Sentence denotes CC50, μMa CPE inhibitionb Reduction in infectious virusc (EC50) Reduction in viral RNA copyd (EC50)
T50 194-308 Sentence denotes Remdesivir adenosine analogue Phase 4 trials for treatment of Ebola or SARS-CoV-2 1809249-37-3 >100 25 23.15 26.90
T51 309-433 Sentence denotes Favipiravir guanineanalogue Approved in Japan and China for treatment of influenza infection 259793-96-9 >100 >100 >100 >100
T52 434-552 Sentence denotes Ribavirin guanosine analogue FDA approved for treatment of chronic hepatitis C infection 36791-04-5 >100 500 >500 >500
T53 553-661 Sentence denotes Galidesivir adenosine analogue Phase 2 trial for yellow fever virus infection 222631-44-9 >100 100 >100 >100
T54 662-766 Sentence denotes R-1479 cytidineanalogue Phase 2 trial for treatment of dengue virus infection 478182-28-4 >100 >100 N.D.
T55 767-771 Sentence denotes N.D.
T56 772-871 Sentence denotes Tenofovor adenosine analogue FDA approved for treatment of HIV-1 and HBV 147127-20-6 >100 >100 N.D.
T57 872-876 Sentence denotes N.D.
T58 877-1009 Sentence denotes Fludarabine phosphate adenosine analogue FDA approved for treatment of B-cell chronic lymphocytic leukemia 75607-67-9 >100 >100 N.D.
T59 1010-1014 Sentence denotes N.D.
T60 1015-1152 Sentence denotes Lopinavir protease inhibitor FDA approved for treatment of HIV-1 infection in combination with ritonavir 192725-17-0 49.75 25 26.63 26.10
T61 1153-1308 Sentence denotes Ritonavir protease inhibitor FDA approved for treatment of HIV-1 infection in combination with other antiretroviral agents 155213-67-5 48.91 >100 >100 >100
T62 1309-1426 Sentence denotes Emetine hydrochloride anti-protozoal Approved in China for severe invasive amoebiasis 316-42-7 56.46 1.5625 0.46 0.50
T63 1427-1564 Sentence denotes Oritavancin diphosphate antibiotics FDA approved treatment for skin infection caused by Gram positive bacteria 192564-14-0 N.D. >100 N.D.
T64 1565-1569 Sentence denotes N.D.
T65 1570-1710 Sentence denotes Dalbavancin hydrochloride antibiotics FDA approved treatment for skin infection caused by Gram positive bacteria 2227366-51-8 N.D. >100 N.D.
T66 1711-1715 Sentence denotes N.D.
T67 1716-1830 Sentence denotes Homoharringtonine anti-cancer FDA approved treatment for chronic myeloid leukemia 26833-87-4 59.75 3.125 2.55 2.14
T68 1831-1968 Sentence denotes Oseltamivir carboxylate antiviral, neuraminidase inhibitor FDA approved treatment for influenza infection 187227-45-8 >100 >100 >100 >100
T69 1969-2098 Sentence denotes Baloxivir acid antiviral, endonuclease inhibitor FDA approved treatment for influenza infection 1985605-59-1 85.90 >100 >100 >100
T70 2099-2231 Sentence denotes Chlorpromazine hydrochloride antagonist for post-synaptic receptors FDA approved treatment for schizophrenia 69-09-0 21.29 >100 N.D.
T71 2232-2236 Sentence denotes N.D.