PMC:7127067 / 6160-9271 JSONTXT 13 Projects

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Id Subject Object Predicate Lexical cue
T46 0-11 Sentence denotes 2 Symptoms
T47 12-112 Sentence denotes The symptoms of COVID-19 infection appear after an incubation period of approximately 5.2 days [12].
T48 113-223 Sentence denotes The period from the onset of COVID-19 symptoms to death ranged from 6 to 41 days with a median of 14 days [8].
T49 224-317 Sentence denotes This period is dependent on the age of the patient and status of the patient's immune system.
T50 318-406 Sentence denotes It was shorter among patients >70-years old compared with those under the age of 70 [8].
T51 407-611 Sentence denotes The most common symptoms at onset of COVID-19 illness are fever, cough, and fatigue, while other symptoms include sputum production, headache, haemoptysis, diarrhoea, dyspnoea, and lymphopenia [5,6,8,13].
T52 612-858 Sentence denotes Clinical features revealed by a chest CT scan presented as pneumonia, however, there were abnormal features such as RNAaemia, acute respiratory distress syndrome, acute cardiac injury, and incidence of grand-glass opacities that led to death [6].
T53 859-1075 Sentence denotes In some cases, the multiple peripheral ground-glass opacities were observed in subpleural regions of both lungs [14] that likely induced both systemic and localized immune response that led to increased inflammation.
T54 1076-1261 Sentence denotes Regrettably, treatment of some cases with interferon inhalation showed no clinical effect and instead appeared to worsen the condition by progressing pulmonary opacities [14] (Fig. 2 ).
T55 1262-1337 Sentence denotes Fig. 2 The systemic and respiratory disorders caused by COVID-19 infection.
T56 1338-1408 Sentence denotes The incubation period of COVID-19 infection is approximately 5.2 days.
T57 1409-1502 Sentence denotes There are general similarities in the symptoms between COVID-19 and previous betacoronavirus.
T58 1503-1696 Sentence denotes However, COVID-19 showed some unique clinical features that include the targeting of the lower airway as evident by upper respiratory tract symptoms like rhinorrhoea, sneezing, and sore throat.
T59 1697-1863 Sentence denotes Additionally, patients infected with COVID-19 developed intestinal symptoms like diarrhoea only a low percentage of MERS-CoV or SARS-CoV patients exhibited diarrhoea.
T60 1864-2071 Sentence denotes It is important to note that there are similarities in the symptoms between COVID-19 and earlier betacoronavirus such as fever, dry cough, dyspnea, and bilateral ground-glass opacities on chest CT scans [6].
T61 2072-2273 Sentence denotes However, COVID-19 showed some unique clinical features that include the targeting of the lower airway as evident by upper respiratory tract symptoms like rhinorrhoea, sneezing, and sore throat [15,16].
T62 2274-2473 Sentence denotes In addition, based on results from chest radiographs upon admission, some of the cases show an infiltrate in the upper lobe of the lung that is associated with increasing dyspnea with hypoxemia [17].
T63 2474-2661 Sentence denotes Importantly, whereas patients infected with COVID-19 developed gastrointestinal symptoms like diarrhoea, a low percentage of MERS-CoV or SARS-CoV patients experienced similar GI distress.
T64 2662-2852 Sentence denotes Therefore, it is important to test faecal and urine samples to exclude a potential alternative route of transmission, specifically through health care workers, patients etc (Fig. 2) [15,16].
T65 2853-3111 Sentence denotes Therefore, development of methods to identify the various modes of transmission such as feacal and urine samples are urgently warranted in order to develop strategies to inhibit and/or minimize transmission and to develop therapeutics to control the disease.