Id |
Subject |
Object |
Predicate |
Lexical cue |
T69 |
77-292 |
Sentence |
denotes |
Shown is the initial entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into cells, primarily type II pneumocytes, after binding to its functional receptor, angiotensin-converting enzyme 2 (ACE2). |
T70 |
293-424 |
Sentence |
denotes |
After endocytosis of the viral complex, surface ACE2 is further down-regulated, resulting in unopposed angiotensin II accumulation. |
T71 |
425-537 |
Sentence |
denotes |
Local activation of the renin–angiotensin–aldosterone system may mediate lung injury responses to viral insults. |
T72 |
538-618 |
Sentence |
denotes |
ACE denotes angiotensin-converting enzyme, and ARB angiotensin-receptor blocker. |