LitCovid-sentences  

PMC:7113610 / 12539-15737 JSONTXT 15 Projects

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Id Subject Object Predicate Lexical cue
T98 0-125 Sentence denotes The genome of the SARS-CoV-2 has been reported over 80% identical to the previous human coronavirus (SARS-like bat CoV) [34].
T99 126-267 Sentence denotes The Structural proteins are encoded by the four structural genes, including spike (S), envelope (E), membrane (M) and nucleocapsid (N) genes.
T100 268-357 Sentence denotes The orf1ab is the largest gene in SARS-CoV-2 which encodes the pp1ab protein and 15 nsps.
T101 358-443 Sentence denotes The orf1a gene encodes for pp1a protein which also contains 10 nsps [34], [35], [36].
T102 444-557 Sentence denotes According to the evolutionary tree, SARS-CoV-2 lies close to the group of SARS-coronaviruses [37], [38] (Fig. 5).
T103 558-763 Sentence denotes Recent studies have indicated notable variations in SARS-CoV and SARS-CoV-2 such as the absence of 8a protein and fluctuation in the number of amino acids in 8b and 3c protein in SARS-CoV-2 [34] (Fig. 4 ).
T104 764-874 Sentence denotes It is also reported that Spike glycoprotein of the Wuhan coronavirus is modified via homologous recombination.
T105 875-973 Sentence denotes The spike glycoprotein of SARS-CoV-2 is the mixture of bat SARS-CoV and a not known Beta-CoV [38].
T106 974-1200 Sentence denotes In a fluorescent study, it was confirmed that the SARS-CoV-2 also uses the same ACE2 (angiotensin-converting enzyme 2) cell receptor and mechanism for the entry to host cell which is previously used by the SARS-CoV [39], [40].
T107 1201-1324 Sentence denotes The single N501T mutation in SARS-CoV-2's Spike protein may have significantly enhanced its binding affinity for ACE2 [33].
T108 1325-1860 Sentence denotes Fig. 4 Betacoronaviruses genome organization; The Betacoronavirus for human (SARS-CoV-2, SARS-CoV and MERS-CoV) genome comprises of the 5′-untranslated region (5′-UTR), open reading frame (orf) 1a/b (green box) encoding non-structural proteins (nsp) for replication, structural proteins including spike (blue box), envelop (maroon box), membrane (pink box), and nucleocapsid (cyan box) proteins, accessory proteins (light gray boxes) such as orf 3, 6, 7a, 7b, 8 and 9b in the SARS-CoV-2 genome, and the 3′-untranslated region (3′-UTR).
T109 1861-1963 Sentence denotes The doted underlined in red are the protein which shows key variation between SARS-CoV-2 and SARS-CoV.
T110 1964-2015 Sentence denotes The length of nsps and orfs are not drawn in scale.
T111 2016-2341 Sentence denotes Fig. 5 Phylogenetic tree of coronaviruses (content in red is the latest addition of newly emerged SARS-CoV-2 and WSFMP Wuhan-Hu-1 is used as a reference in the tree); The phylogenetic tree showing the relationship of Wuhan-Hu-1 (denoted as red) to selected coronavirus is based on nucleotide sequences of the complete genome.
T112 2342-2401 Sentence denotes The viruses are grouped into four genera (prototype shown):
T113 2402-2514 Sentence denotes Alphacoronavirus (sky blue), Betacoronavirus (pink), Gammacoronavirus (green) and Deltacoronavirus (light blue).
T114 2515-2630 Sentence denotes Subgroup clusters are labeled as 1a and 1b for the Alphacoronavirus and 2a, 2b, 2c, and 2d for the Betacoronavirus.
T115 2631-3133 Sentence denotes This tree is based on the published trees of Coronavirinae [3], [41] and reconstructed with sequences of the complete RNA- dependent RNA polymerase- coding region of the representative novel coronaviruses (maximum likelihood method using MEGA 7.2 software). severe acute respiratory syndrome coronavirus (SARS- CoV); SARS- related coronavirus (SARSr- CoV); the Middle East respiratory syndrome coronavirus (MERS- CoV); porcine enteric diarrhea virus (PEDV); Wuhan seafood market pneumonia (Wuhan-Hu-1).
T116 3134-3198 Sentence denotes Bat CoV RaTG13 Showed high sequence identity to SARS-CoV-2 [42].