PMC:7113610 / 11641-12504 JSONTXT 12 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T90 0-124 Sentence denotes Fig. 3 The life cycle of SARS-CoV-2 in host cells; begins its life cycle when S protein binds to the cellular receptor ACE2.
T91 125-277 Sentence denotes After receptor binding, the conformation change in the S protein facilitates viral envelope fusion with the cell membrane through the endosomal pathway.
T92 278-326 Sentence denotes Then SARS-CoV-2 releases RNA into the host cell.
T93 327-464 Sentence denotes Genome RNA is translated into viral replicase polyproteins pp1a and 1ab, which are then cleaved into small products by viral proteinases.
T94 465-601 Sentence denotes The polymerase produces a series of subgenomic mRNAs by discontinuous transcription and finally translated into relevant viral proteins.
T95 602-755 Sentence denotes Viral proteins and genome RNA are subsequently assembled into virions in the ER and Golgi and then transported via vesicles and released out of the cell.
T96 756-863 Sentence denotes ACE2, angiotensin-converting enzyme 2; ER, endoplasmic reticulum; ERGIC, ER–Golgi intermediate compartment.