Id |
Subject |
Object |
Predicate |
Lexical cue |
T11 |
0-8 |
Sentence |
denotes |
Results: |
T12 |
9-189 |
Sentence |
denotes |
We report in silico identification of a comprehensive list of immunogenic peptides that can be used as potential targets for 2019 novel coronavirus (2019-nCoV) vaccine development. |
T13 |
190-370 |
Sentence |
denotes |
First, we found 28 nCoV peptides identical to Severe acute respiratory syndrome-related coronavirus (SARS CoV) that have previously been characterized immunogenic by T cell assays. |
T14 |
371-519 |
Sentence |
denotes |
Second, we identified 48 nCoV peptides having a high degree of similarity with immunogenic peptides deposited in The Immune Epitope Database (IEDB). |
T15 |
520-874 |
Sentence |
denotes |
Lastly, we conducted a de novo search of 2019-nCoV 9-mer peptides that i) bind to common HLA alleles in Chinese and European population and ii) have T Cell Receptor (TCR) recognition potential by positional weight matrices and a recently developed immunogenicity algorithm, iPred, and identified in total 63 peptides with a high immunogenicity potential. |