PMC:7110798 / 8675-11448 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T75 0-22 Sentence denotes Results and discussion
T76 23-115 Sentence denotes The exponential growth fitting results are shown in Figure 1(b), (d), (f), (h), (j) and (l).
T77 116-318 Sentence denotes The coefficient of determination, R-squared, ranges from 0.91 to 0.92 for all reporting rate changing scenarios, which implies that the early outbreak data were largely following the exponential growth.
T78 319-381 Sentence denotes In Table 1, we estimated that the R 0 ranges from 2.24 (95%CI:
T79 382-408 Sentence denotes 1.96-2.55) to 5.71 (95%CI:
T80 409-487 Sentence denotes 4.24-7.54) associated with an 8-fold to 0-fold increase in the reporting rate.
T81 488-601 Sentence denotes All R 0 estimates are significantly larger than 1, which indicates the potential of 2019-nCoV to cause outbreaks.
T82 602-796 Sentence denotes Since the official diagnostic protocol was released by WHO on January 17 (World Health Organization, 2020b), an increase in the diagnosis and reporting of 2019-nCoV infections probably occurred.
T83 797-978 Sentence denotes Thereafter, the daily number of newly reported cases started increasing around January 17, see Figure 1, which implies that more infections were likely being diagnosed and recorded.
T84 979-1171 Sentence denotes We suggested that changes in reporting might exist, and thus it should be considered in the estimation, i.e., 8-, 4- and 2-fold changes are more likely than no change in the reporting efforts.
T85 1172-1385 Sentence denotes Although six scenarios about the reporting rate were explored in this study, the real situation is difficult to determine given limited data and (almost) equivalent model fitting performance in terms of R-squared.
T86 1386-1481 Sentence denotes However, with increasing reporting rate, we found the mean R 0 is likely to be between 2 and 3.
T87 1482-1601 Sentence denotes Our analysis and estimation of R 0 rely on the accuracy of the SI of 2019-nCoV, which remains unknown as of January 25.
T88 1602-1692 Sentence denotes In this work, we employed the SIs of SARS and MERS as approximations to that of 2019-nCoV.
T89 1693-1930 Sentence denotes The determination of SI requires knowledge of the chain of disease transmission that needs a sufficient number of patient samples and periods of time for follow-up (Cowling et al., 2009), and thus this is unlikely to be achieved shortly.
T90 1931-2087 Sentence denotes However, using SIs of SARS and MERS as approximation could provide an insight to the transmission potential of 2019-nCoV at the early stage of the outbreak.
T91 2088-2358 Sentence denotes We reported that the mean R 0 of 2019-nCoV is likely to be from 2.24 (8-fold) to 3.58 (2-fold), and it is largely in the range of those of SARS, i.e., 2-5 (Bauch et al., 2005, Lipsitch et al., 2003, Wallinga and Teunis, 2004), and MERS, i.e., 2.7-3.9 (Lin et al., 2018).
T92 2359-2555 Sentence denotes We note that WHO reported the basic reproduction number for the human-to-human (direct) transmission ranged from 1.4 to 2.5 (World Health Organization, 2020b), which is marginally lower than ours.
T93 2556-2773 Sentence denotes However, many of the existing online preprints estimate the mean R 0 ranging from 2 to 5 (Imai et al., 2020, Riou and Althaus, 2020, Read et al., 2020, Shen et al., 2020), which is largely consistent with our results.