| T603 |
0-574 |
Sentence |
denotes |
[75] Treatment with lopinavir/ritonavir or interferon-beta1b improves outcome of MERSCoV infection in a nonhuman primate model of common marmoset Chan et al Hong Kong/China 2015 (In vivo)The authors assessed 3 repurposed drugs with potent in vitro anti-MERS-CoV activity (mycophenolate mofetil, lopinavir/ritonavir, and interferon-β1b) in common marmosets with severe disease resembling MERS in humans.all MMF-treated animals developed severe and/or fatal disease with higher mean viral loads.The authors concluded that MMF alone may worsen MERS and should not be used. |
