LitCovid-sentences  

PMC:7103735 / 4657-6266 JSONTXT 12 Projects

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Id Subject Object Predicate Lexical cue
T40 0-69 Sentence denotes Avian infectious bronchitis virus was the first CoV isolated in 1930.
T41 70-204 Sentence denotes Different CoVs were subsequently isolated in infected rodents and domestic animals, including mouse, pig, cow, turkey, cats, and dogs.
T42 205-453 Sentence denotes CoVs were once believed not to cause human disease, but this was changed after the successful isolation of HCoV strain B814 from the clinical specimen of patients with common cold by serial passage of inoculum in tracheal organ culture in 1962 [2].
T43 454-569 Sentence denotes In the 1960s, several novel HCoVs were described but no further characterization was performed in most cases [3,4].
T44 570-728 Sentence denotes 229E and OC43 were known as causative agents of the common cold and upper respiratory tract infection, accounting for up to 30% of cases with common cold [4].
T45 729-794 Sentence denotes 229E is a prototype strain isolated using tracheal organ culture.
T46 795-892 Sentence denotes OC43 was isolated from organ culture and subsequent serial passage in the brain of suckling mice.
T47 893-990 Sentence denotes The clinical features of 229E and OC43 infection were characterized in human volunteer study [4].
T48 991-1077 Sentence denotes In most cases, natural infection with HCoVs results in mild common cold-like symptoms.
T49 1078-1167 Sentence denotes Severe lower respiratory tract infection develops only in immunocompromised patients [5].
T50 1168-1372 Sentence denotes Apart from a respiratory infection, 229E and OC43 were suspected to infect the central nervous system (CNS) as mRNA and CoV-like particles were detected in CNS samples of patients with multiple sclerosis.
T51 1373-1481 Sentence denotes This claim was further supported by the susceptibility of human neural primary culture to 229E and OC43 [6].
T52 1482-1609 Sentence denotes However, the influence of 229E and OC43 on the development and progression of multiple sclerosis awaits further investigations.