Id |
Subject |
Object |
Predicate |
Lexical cue |
T113 |
0-361 |
Sentence |
denotes |
In an effort to identify the direct animal source of SARS-CoV, SARS-CoV-related CoVs (SARS-rCoV), which share 99.8% sequence homology at the nucleotide level with SARS-CoV, were isolated in 2003 from workers working in a live animal market where animal meats were sold and from animals in the same market [28], including Himalayan palm civets and a raccoon dog. |
T114 |
362-490 |
Sentence |
denotes |
Palm civets were once thought to be the natural host of SARS-CoV as anti-SARS-CoV antibody was detected in civets in the market. |
T115 |
491-576 |
Sentence |
denotes |
In experimental infection, civets were equally susceptible to SARS-CoV and SARS-rCoV. |
T116 |
577-622 |
Sentence |
denotes |
Infected animals displayed clinical symptoms. |
T117 |
623-793 |
Sentence |
denotes |
However, no anti-SARS-CoV antibodies were detected in any wild or farmed civets [29], raising the possibility that they are not a natural host of SARS-CoV and SARS-rCoVs. |
T118 |
794-874 |
Sentence |
denotes |
In 2005, horseshoe bats were identified as a natural host of SARS-rCoVs [30,31]. |
T119 |
875-958 |
Sentence |
denotes |
These bat SARS-rCoVs serve as the gene pool and an evolutionary origin of SARS-CoV. |
T120 |
959-1075 |
Sentence |
denotes |
It is particularly noteworthy that a SARS-rCoV using the same ACE2 receptor as SARS-CoV was also found in bats [32]. |
T121 |
1076-1129 |
Sentence |
denotes |
Their genomes share 95% nucleotide sequence homology. |
T122 |
1130-1254 |
Sentence |
denotes |
Presumably, palm civets and other mammals in the market were transiently infected, and they transmitted the virus to humans. |
T123 |
1255-1401 |
Sentence |
denotes |
It remains to be clarified whether another stable and natural reservoir host of SARS-CoV, exactly like dromedary camels for MERS-CoV, might exist. |