Id |
Subject |
Object |
Predicate |
Lexical cue |
T37 |
0-129 |
Sentence |
denotes |
Patients at this phase will begin to develop the hypercoagulable state and D-Dimer-based coagulation factors may appear abnormal. |
T38 |
130-288 |
Sentence |
denotes |
The use of IVIG at this time may provide patients with effective clinical benefits and inhibit the formation of inflammatory factors storm (“cytokine storm”). |
T39 |
289-456 |
Sentence |
denotes |
LWMH therapy, suggested by colleagues at the Department of Hematology, Peking Union Medical College Hospital, may also alleviate the hypercoagulable state in patients. |
T40 |
457-685 |
Sentence |
denotes |
During the development of dyspnoea and chest imaging changes from light to severe, the D-dimer increased from mild to significant, along with prolonged prothrombin time (PT) and gradual decrease of fibrinogen (FBG) and platelet. |
T41 |
686-913 |
Sentence |
denotes |
Recently, it has been observed that some of the non-survivors suffered from ischaemic changes such as ecchymosis of the fingers and toes (Figure 1), at the same time as the organ functions of the heart and kidneys became worse. |
T42 |
914-1009 |
Sentence |
denotes |
The above manifestations are consistent with the diagnosis of the hypercoagulable phase of DIC. |
T43 |
1010-1139 |
Sentence |
denotes |
It is believed that COVID-2019 can activate coagulation cascade through various mechanisms, leading to severe hypercoagulability. |
T44 |
1140-1272 |
Sentence |
denotes |
Early anticoagulation may block clotting formation and reduce microthrombus, thereby reducing the risk of major organ damages [5,6]. |
T45 |
1273-1282 |
Sentence |
denotes |
Figure 1. |
T46 |
1283-1330 |
Sentence |
denotes |
Ecchymosis in severe type of COVID-19 patients. |