PMC:7103696 / 4126-5484 JSONTXT 13 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T36 0-27 Sentence denotes Abnormal coagulation status
T37 28-157 Sentence denotes Patients at this phase will begin to develop the hypercoagulable state and D-Dimer-based coagulation factors may appear abnormal.
T38 158-316 Sentence denotes The use of IVIG at this time may provide patients with effective clinical benefits and inhibit the formation of inflammatory factors storm (“cytokine storm”).
T39 317-484 Sentence denotes LWMH therapy, suggested by colleagues at the Department of Hematology, Peking Union Medical College Hospital, may also alleviate the hypercoagulable state in patients.
T40 485-713 Sentence denotes During the development of dyspnoea and chest imaging changes from light to severe, the D-dimer increased from mild to significant, along with prolonged prothrombin time (PT) and gradual decrease of fibrinogen (FBG) and platelet.
T41 714-941 Sentence denotes Recently, it has been observed that some of the non-survivors suffered from ischaemic changes such as ecchymosis of the fingers and toes (Figure 1), at the same time as the organ functions of the heart and kidneys became worse.
T42 942-1037 Sentence denotes The above manifestations are consistent with the diagnosis of the hypercoagulable phase of DIC.
T43 1038-1167 Sentence denotes It is believed that COVID-2019 can activate coagulation cascade through various mechanisms, leading to severe hypercoagulability.
T44 1168-1300 Sentence denotes Early anticoagulation may block clotting formation and reduce microthrombus, thereby reducing the risk of major organ damages [5,6].
T45 1301-1310 Sentence denotes Figure 1.
T46 1311-1358 Sentence denotes Ecchymosis in severe type of COVID-19 patients.