| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T78 |
0-41 |
Sentence |
denotes |
2.1.1 Role of underling CV comorbidities |
| T79 |
42-213 |
Sentence |
denotes |
The patients with pre-existing CVD appear to have heightened vulnerability to develop COVID-19 and tend to have more severe disease with worse clinical outcomes [1,4,6,8]. |
| T80 |
214-366 |
Sentence |
denotes |
Various CV risk factors also adversely affect porgnosis of these patients, although they do not seem to increase likleihood of developing the infection. |
| T81 |
367-577 |
Sentence |
denotes |
A meta-analysis of six published studies from China including 1527 patients with COVID-19 reported 9.7%, 16.4% and 17.1% prevalence of diabetes, cardio-cerebrovascular disease and hypertension respectively [4]. |
| T82 |
578-766 |
Sentence |
denotes |
Although the prevalence of diabetes and hypertension in this cohort was same as in the Chinese general population, the prevalence of cardio-cerebrovascular disease was considerably higher. |
| T83 |
767-1040 |
Sentence |
denotes |
More importantly, the presence of diabetes, cardio-cerebrovascular disease and hypertension was associated with a 2-fold, 3-fold and 2-fold greater risk of severe disease or requiring intensive care unit (ICU) admission, suggesting prognostic impact of these comorbidities. |
| T84 |
1041-1190 |
Sentence |
denotes |
A much larger report from the Chinese Center for Disease Control and Prevention described clinical outcomes in 44672 confirmed cases of COVID-19 [1]. |
| T85 |
1191-1365 |
Sentence |
denotes |
The overall case fatality rate (CFR) was 2.3% in the entire cohort but significantly higher (6%, 7.3% and 10.5% respectively) in patients with hypertension, diabetes and CVD. |
| T86 |
1366-1537 |
Sentence |
denotes |
Although data is lacking, the prevalence of various CV comorbidities and their impact on clinical outcomes seem to vary considerably across different geographic locations. |
| T87 |
1538-1665 |
Sentence |
denotes |
The CFRs have been lower in China outside Hubei province and many other countries but much higher in some European nations [2]. |
| T88 |
1666-1788 |
Sentence |
denotes |
A small report including 21 patients from Washington, United States of America presented a particularly grim scenario [9]. |
| T89 |
1789-1900 |
Sentence |
denotes |
Comorbidities were common in this cohort, with diabetes present in 33.3% and congestive heart failure in 42.9%. |
| T90 |
1901-1978 |
Sentence |
denotes |
Acute cardiac dysfunction occurred in 33.3% patients and 52.4% patients died. |
| T91 |
1979-2218 |
Sentence |
denotes |
However, the overall CFR in the United States seems to be much lower (201 deaths out of 15219 confirmed cases) [2], although it is likely to rise as many of the patients are currently hospitalized and have not yet had the definite outcome. |
