Id |
Subject |
Object |
Predicate |
Lexical cue |
T3 |
0-221 |
Sentence |
denotes |
One of the most perplexing questions regarding the current COVID-19 coronavirus epidemic is the discrepancy between the severity of cases observed in the Hubei province of China and those occurring elsewhere in the world. |
T4 |
222-341 |
Sentence |
denotes |
One possible answer is antibody dependent enhancement (ADE) of SARS-CoV-2 due to prior exposure to other coronaviruses. |
T5 |
342-519 |
Sentence |
denotes |
ADE modulates the immune response and can elicit sustained inflammation, lymphopenia, and/or cytokine storm, one or all of which have been documented in severe cases and deaths. |
T6 |
520-724 |
Sentence |
denotes |
ADE also requires prior exposure to similar antigenic epitopes, presumably circulating in local viruses, making it a possible explanation for the observed geographic limitation of severe cases and deaths. |