Id |
Subject |
Object |
Predicate |
Lexical cue |
T21 |
0-12 |
Sentence |
denotes |
Introduction |
T22 |
13-272 |
Sentence |
denotes |
Since December 2019, an increasing number of pneumonia cases caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, Hubei, China, and subsequently, an outbreak of coronavirus disease 2019 (COVID-19) swept the globe [1–4]. |
T23 |
273-437 |
Sentence |
denotes |
As of February 3, 2020, more than 23,214 suspected cases and 20,438 confirmed cases have been identified, and there has been over 425 deaths related to the illness. |
T24 |
438-497 |
Sentence |
denotes |
Moreover, the virus is still spreading at an alarming rate. |
T25 |
498-615 |
Sentence |
denotes |
In this sudden epidemic, reverse transcription polymerase chain reaction (RT-PCR) revealed the cause of the outbreak. |
T26 |
616-711 |
Sentence |
denotes |
The SARS-CoV-2 can be specifically detected in respiratory secretions or plasma samples RT-PCR. |
T27 |
712-940 |
Sentence |
denotes |
However, some patients with likely COVID-19 may have negative initial RT-PCR results for COVID-19, which may be due to insufficient cellular material for detection or improper extraction of nucleic acids from clinical materials. |
T28 |
941-1239 |
Sentence |
denotes |
Thus, imaging examination, which can effectively and conveniently observe the pulmonary parenchymal abnormalities, can solve some challenges associated with clinical diagnosis in suspected patients with a false-negative result, especially symptomatic patients with dyspnea and respiratory distress. |
T29 |
1240-1363 |
Sentence |
denotes |
Because this infection is caused by the unprecedented SARS-CoV-2, few related imaging studies have been currently reported. |
T30 |
1364-1510 |
Sentence |
denotes |
Among the studies that have been conducted, multifocal consolidation or ground-glass opacity (GGO) was observed on chest radiographs and CT [5–7]. |
T31 |
1511-1890 |
Sentence |
denotes |
However, the sensitivity of chest radiographs for pneumonia are relatively low, and it is difficult to use chest radiographs to distinguish COVID-19 from common pneumonia during the cold season and pneumonia caused by other coronaviruses, such as severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) infections [8]. |
T32 |
1891-1976 |
Sentence |
denotes |
In addition, the disease is developing rapidly and the symptoms of this disease vary. |
T33 |
1977-2244 |
Sentence |
denotes |
Hence, it is very necessary to systematically analyze the chest CT findings associated with this disease systematically, for the timely isolation, COVID-19 RT-PCR and respiratory care of patients, and early implementation of infection prevention and control measures. |
T34 |
2245-2518 |
Sentence |
denotes |
To fully understand and early discriminate the CT features of this disease in its early stages, we collected initial chest CT data from confirmed COVID-19 patients who did not receive any antiviral treatment mainly from Chongqing Three Gorges Central Hospital for analysis. |
T35 |
2519-2802 |
Sentence |
denotes |
The Chongqing Three Gorges Central Hospital, located in the northeast of Chongqing and connected to Hubei Province, is one of the designated hospitals for the centralized treatment of pneumonia patients infected by the SARS-CoV-2 and has received a large number of COVID-19 patients. |
T36 |
2803-3037 |
Sentence |
denotes |
Therefore, our aim was to systematically analyze the CT features of the early and progressive stages of the natural course of COVID-19 and explore the possible pathological changes in the lung during different periods of this disease. |