LitCovid-sentences  

PMC:7095246 / 17598-23431 JSONTXT 15 Projects

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Id Subject Object Predicate Lexical cue
T206 0-11 Sentence denotes Discussions
T207 12-73 Sentence denotes COVID-19 is a new disease which is caused by betacoronavirus.
T208 74-432 Sentence denotes The diameter of the virus particle is very small, about 60~140 nm; therefore, it is easy to reach the lung terminal structure, such as alveolar septum, alveolar wall, and interlobular septum, which causes extensive edema and lymphocyte infiltration in the lung interstitium; early alveolar exudation is not prominent, but the disease progresses rapidly [16].
T209 434-450 Sentence denotes Imaging features
T210 451-730 Sentence denotes In this study, the imaging features were consistent with the previous literature reports [9–13, 16–18] of viral pneumonia; most of the patients had ground-glass opacities and mixed ground-glass opacities; no patients demonstrated consolidation without ground-glass opacification.
T211 731-766 Sentence denotes Subpleural distribution was common.
T212 767-818 Sentence denotes It also occurred around the bronchovascular bundle.
T213 819-890 Sentence denotes Air bronchograms and interlobular septal thickening were often present.
T214 891-962 Sentence denotes No patients had cavitation, centrilobular nodules, and lymphadenopathy.
T215 963-1031 Sentence denotes Pleural effusion was rare and most of them occurred in severe cases.
T216 1032-1214 Sentence denotes Most of the lesions involved both lower lobes (85.7%), most of them more than two lobes (74%), and bilateral involvement was common (83.3%); single lobe involvement was rare (10.3%).
T217 1216-1249 Sentence denotes CT visual quantitative evaluation
T218 1250-1546 Sentence denotes In a recent study done by Michael et al, they introduced a method to score the severity of inflammation on CT images based on summing up degree of acute lung inflammation lesions involvement of each lobe (including ground-glass opacity or consolidation or other fuzzy interstitial opacities) [9].
T219 1547-1652 Sentence denotes We used the same method to quantify pulmonary inflammation and correlate to the clinical classifications.
T220 1653-1753 Sentence denotes There was significant difference in scores between common type and severe-critical type (p < 0.001).
T221 1754-1941 Sentence denotes However, there was also a score overlap between the two groups, which showed that 8 cases in the common type had a higher score, and 5 cases in the severe-critical type had a lower score.
T222 1942-2186 Sentence denotes Among 8 cases of common type, 7 cases had fibrotic lesions which indicated that the lesions began to be repaired, and all of the 8 patients were less than 70 years old (range 36–65, average 52.5 years), none of them had pulmonary complications.
T223 2187-2289 Sentence denotes The specific situation of 5 patients in a severe-critical type which had a lower score was as follows:
T224 2290-2848 Sentence denotes 3 of the 5 patients were over 70 years old; among them, 1 patient was a female smoker with diabetes, aged 80 years old, with moderate emphysema and a small amount of pleural effusion; 1 patient was a 70-year-old female, with emphysema and a small amount of pleural effusion as well; the other one was 75-year-old female with high blood pressure; the forth case was a 44-year-old male without any underlying disease; however, CT images showed only progressive lesions such as ground-glass opacification and consolidation without any fibrotic lesions (Fig. 5).
T225 2849-2991 Sentence denotes The last case was a 58-year-old female without any underlying disease; further analysis was needed to find out the cause of clinical severity.
T226 2992-3178 Sentence denotes Overall, we believe that many factors, such as advanced age, underlying diseases, and pleural effusions, would relate to the clinical severity, which call for a comprehensive evaluation.
T227 3179-3295 Sentence denotes Fig. 5 A 44-year-old male was admitted to the hospital 1 day after fever and cough with a body temperature of 39 °C.
T228 3296-3354 Sentence denotes The leukocytes were normal and lymphocytes were decreased.
T229 3355-3472 Sentence denotes He was living in Zhuhai and traveled to Macao 12 days before the onset of the disease and stayed in Macao for 1 week.
T230 3473-3502 Sentence denotes He was healthy and nonsmoker.
T231 3503-3635 Sentence denotes Chest CT (images a–c) on the 4th day after admission demonstrated bilateral peripheral ground-glass opacities without consolidation.
T232 3636-3646 Sentence denotes TSS was 9.
T233 3647-3690 Sentence denotes The clinical type was severe-critical type.
T234 3691-3835 Sentence denotes Follow-up CT (images d, e) on the 22nd day after onset showed bilateral fibrotic changes with traction bronchiectasis and ground-grass opacities
T235 3837-3874 Sentence denotes High proportion of mild-type patients
T236 3875-4036 Sentence denotes Among the 78 cases, there were 24 cases of mild type (30.8%) which mean those patients had positive real-time RT-PCR SARS-CoV-2 tests, while chest CT was normal.
T237 4037-4193 Sentence denotes In the review of several recent published literature of COVID-19 in Wuhan, China, all patients reported in articles had ground-glass opacities in the lungs.
T238 4194-4266 Sentence denotes Huang et al reported 41 infected cases in Wuhan, all had pneumonias [1].
T239 4267-4378 Sentence denotes Chen et al reported 99 confirmed cases in Wuhan with 74 bilateral pneumonias and 25 unilateral pneumonias [19].
T240 4379-4525 Sentence denotes However, the most recent report from Guangzhou had similar findings, which showed 23.6% confirmed patients without abnormalities on chest CT [20].
T241 4526-4588 Sentence denotes To further explore our data, we found several characteristics.
T242 4589-4761 Sentence denotes Nine cases had a short time interval from onset to the latest CT examination with a range of 0–7 days, which indicated that the chest CT could be normal at the early phase.
T243 4762-4864 Sentence denotes Another 9 cases had a longer time interval from onset to the latest CT scan with a range of 8–19 days.
T244 4865-4928 Sentence denotes The negative findings may not relate to the shorter onset time.
T245 4929-5044 Sentence denotes It remains to be further explored whether the CT negativity may relate to the degree of infection and autoimmunity.
T246 5045-5090 Sentence denotes Finally, the last 6 patients had no symptoms.
T247 5091-5253 Sentence denotes These patients were negative in both clinical and imaging, suggesting that some cases were potential sources of infection, which should be paid more attention to.
T248 5255-5265 Sentence denotes Limitation
T249 5266-5469 Sentence denotes In this study, the number of cases between groups was significantly different because too few severe-critical patients were included in this study, which decreased the reliability of statistical results.
T250 5470-5671 Sentence denotes Only image analysis was carried out without combining clinical information in this study; however, advanced age, underlying diseases, and pleural effusions may lead to a lower TSS but severe situation.
T251 5672-5833 Sentence denotes In our next study, we will include more cases, and make a comprehensive evaluation combining the clinical characteristics and laboratory examination information.