Id |
Subject |
Object |
Predicate |
Lexical cue |
T180 |
0-71 |
Sentence |
denotes |
Figure 5 Structures of MERS-CoV N-NTD complexed with potent compounds. |
T181 |
72-560 |
Sentence |
denotes |
The structures were solved using HCoV-OC43 N-NTD (PDB:4J3K) as the search model.24 Left panel: (Upper) structural superimposition of the MERS-CoV N-NTD:P1 complex (monomers 1 and 2 are in purple and pink, respectively) and the MERS-CoV N-NTD:P3 complex (monomers 1 and 2 are in brown and green, respectively) with compounds depicted as stick structures. (Lower) Interactions involving vector-fusion residues in the non-native dimer of the apoprotein shown for comparison with (A) and (B). |
T182 |
561-595 |
Sentence |
denotes |
Color is the same as in Figure 1A. |
T183 |
596-680 |
Sentence |
denotes |
Right panel: detailed interactions among MERS-CoV N-NTD and P1 (A, B) and P3 (C, D). |
T184 |
681-791 |
Sentence |
denotes |
Different Fo–Fc maps were contoured at ∼2.5 σ. (A) Detailed stereoview of interactions at the P1-binding site. |
T185 |
792-851 |
Sentence |
denotes |
The color of each monomer is the same as in the left panel. |
T186 |
852-974 |
Sentence |
denotes |
Residues constructing the P1-binding pocket are labeled and showed as sticks. (B) Schematic of P1 bound to MERS-CoV N-NTD. |
T187 |
975-1054 |
Sentence |
denotes |
Hydrophobic contacts between P1 and each monomer are displayed as dashed lines. |
T188 |
1055-1172 |
Sentence |
denotes |
Nonbonding interactions are indicated by cyan arrows. (C) Detailed stereoview of interactions at the P3-binding site. |
T189 |
1173-1232 |
Sentence |
denotes |
The color of each monomer is the same as in the left panel. |
T190 |
1233-1354 |
Sentence |
denotes |
Residues belonging to the P3-binding pocket are labeled and shown as sticks. (D) Schematic of P3 bound to MERS-CoV N-NTD. |
T191 |
1355-1434 |
Sentence |
denotes |
Hydrophobic contacts between P3 and each monomer are displayed as dashed lines. |
T192 |
1435-1487 |
Sentence |
denotes |
Nonbonding interactions are indicated by red arrows. |