| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T4 |
0-64 |
Sentence |
denotes |
Many human viral diseases are a consequence of a zoonotic event. |
| T5 |
65-244 |
Sentence |
denotes |
Some of the diseases caused by these zoonotic events have affected millions of people around the world, some of which have resulted in high rates of morbidity/mortality in humans. |
| T6 |
245-363 |
Sentence |
denotes |
Changes in the viral proteins that function as ligands of the host receptor may promote the spillover between species. |
| T7 |
364-507 |
Sentence |
denotes |
The most recent of these zoonotic events that have caused an ongoing epidemic of high magnitude is the Covid-19 epidemics caused by SARS-CoV-2. |
| T8 |
508-669 |
Sentence |
denotes |
The aim of this study was to determine the mutation(s) in the sequence of the spike protein of the SARS-CoV-2 that might be favoring human to human transmission. |
| T9 |
670-791 |
Sentence |
denotes |
An in silico approach was performed, and changes were detected in the S1 subunit of the receptor-binding domain of spike. |
| T10 |
792-973 |
Sentence |
denotes |
The observed changes have significant effect on SARS-CoV-2 spike/ACE2 interaction and produce a reduction in the binding energy, compared to the one of the Bat-CoV to this receptor. |
| T11 |
974-1139 |
Sentence |
denotes |
The data presented in this study suggest a higher affinity of the SARS-Cov-2 spike protein to the human ACE2 receptor, compared to the one of Bat-CoV spike and ACE2. |
| T12 |
1140-1214 |
Sentence |
denotes |
This could be the cause of the rapid viral spread of SARS-CoV-2 in humans. |
