Id |
Subject |
Object |
Predicate |
Lexical cue |
T168 |
0-10 |
Sentence |
denotes |
Discussion |
T169 |
11-215 |
Sentence |
denotes |
Considering that the majority of patients had a clear history of exposure in Wuhan or to infected patients, our data confirmed that SARS-CoV-2 has the ability for person-to-person transmission [6, 9, 10]. |
T170 |
216-279 |
Sentence |
denotes |
Infected patients predominantly presented with fever and cough. |
T171 |
280-326 |
Sentence |
denotes |
Notably, some patients (7%) were asymptomatic. |
T172 |
327-433 |
Sentence |
denotes |
These findings indicated that the absence of clinical symptoms cannot rule out the diagnosis of infection. |
T173 |
434-609 |
Sentence |
denotes |
Persons with a clear history of exposure to SARS-CoV-2, regardless of clinical symptoms, should be considered for medical observation, home isolation, and further examination. |
T174 |
610-716 |
Sentence |
denotes |
Similarly, patients with symptoms without a known history of exposure should undergo further examinations. |
T175 |
717-808 |
Sentence |
denotes |
The numbers of patients infected with SARS-CoV-2 is rapidly increasing nationwide in China. |
T176 |
809-1023 |
Sentence |
denotes |
Chest CT can detect lung abnormalities with high sensitivity, which is quite helpful for early diagnosis of the disease that can trigger early treatment, which facilitates the containment of this emergency disease. |
T177 |
1024-1194 |
Sentence |
denotes |
Our study showed some common CT imaging features in patients affected by SARS-CoV-2 pneumonia: bilateral, multifocal ground glass opacities, with peripheral distribution. |
T178 |
1195-1312 |
Sentence |
denotes |
Of note, more than half of the patients had multilobar involvement and lesions were more frequent in the lower lobes. |
T179 |
1313-1464 |
Sentence |
denotes |
Pleural effusion, pericardial effusion, cavitation, thoracic lymphadenopathy, and pulmonary emphysema were uncommon imaging findings in these patients. |
T180 |
1465-1557 |
Sentence |
denotes |
Imaging features of viruses’ infections usually appear as multifocal ground glass opacities. |
T181 |
1558-1683 |
Sentence |
denotes |
A previous study identified that ground glass opacities on CT images correspond to pathological diffuse alveolar damage [11]. |
T182 |
1684-1793 |
Sentence |
denotes |
Histologically, the opacity of ground glass may be caused by alveoli filled with blood, pus, water, or cells. |
T183 |
1794-1893 |
Sentence |
denotes |
The CT imaging features of viral pneumonia are associated with the pathogenesis of viral infection. |
T184 |
1894-2023 |
Sentence |
denotes |
Most viral pneumonia shares similar imaging features in the same Viridae family because of similarities in the pathogenesis [12]. |
T185 |
2024-2171 |
Sentence |
denotes |
SARS-CoV-2 belongs to the family Coronaviridae, so, as expected, the imaging features of SARS-CoV-2 are similar to SARS-CoV and MERS-CoV infection. |
T186 |
2172-2296 |
Sentence |
denotes |
Nonetheless, unilateral involvement is more common than multifocal involvement in the early phase of SARS and MERS [13, 14]. |
T187 |
2297-2452 |
Sentence |
denotes |
In our study, the majority of patients showed multifocal involvement in the initial chest CT scan, and this finding is consistent with a recent report [8]. |
T188 |
2453-2619 |
Sentence |
denotes |
However, whether this finding is a characteristic feature of the SARS-CoV-2 distinguished from the other two coronaviruses remains to be confirmed by further studies. |
T189 |
2620-2779 |
Sentence |
denotes |
The follow-up CT examination in 52 patients showed that 3 patients who had negative baseline scan, rapidly progressed to with bilateral ground glass opacities. |
T190 |
2780-2942 |
Sentence |
denotes |
Since there is an incubation period after infection with the SARS-CoV-2 [15], a patient may not present any symptoms and imaging abnormalities during this period. |
T191 |
2943-3037 |
Sentence |
denotes |
At present, real-time PCR is used to confirm SARS-CoV-2 infection from respiratory secretions. |
T192 |
3038-3172 |
Sentence |
denotes |
In our study, few patients initially negative for SARS-CoV-2 nucleic acid test had bilateral ground glass opacities in chest CT scans. |
T193 |
3173-3272 |
Sentence |
denotes |
After a few days, patients converted to positive for SARS-CoV-2 nucleic acid test by real-time PCR. |
T194 |
3273-3443 |
Sentence |
denotes |
This points out that patient’s history, clinical manifestations, imaging characteristics, and laboratory tests are all important elements in the diagnosis of the disease. |
T195 |
3444-3475 |
Sentence |
denotes |
Our study had some limitations. |
T196 |
3476-3632 |
Sentence |
denotes |
First of all, we cannot demonstrate any prognostic role for chest CT, because we did not find any correlation between imaging and the course of the disease. |
T197 |
3633-3713 |
Sentence |
denotes |
Also, 52 patients with short-term follow-up chest CT showed disease progression. |
T198 |
3714-3949 |
Sentence |
denotes |
The imaging evaluation of disease progression is not complete, and we will collect more follow-up CT data to observe the evolution and outcome of the disease and provide more imaging information to be correlated with clinical findings. |