PMC:7080117 / 12573-16522 JSONTXT 14 Projects

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Id Subject Object Predicate Lexical cue
T168 0-10 Sentence denotes Discussion
T169 11-215 Sentence denotes Considering that the majority of patients had a clear history of exposure in Wuhan or to infected patients, our data confirmed that SARS-CoV-2 has the ability for person-to-person transmission [6, 9, 10].
T170 216-279 Sentence denotes Infected patients predominantly presented with fever and cough.
T171 280-326 Sentence denotes Notably, some patients (7%) were asymptomatic.
T172 327-433 Sentence denotes These findings indicated that the absence of clinical symptoms cannot rule out the diagnosis of infection.
T173 434-609 Sentence denotes Persons with a clear history of exposure to SARS-CoV-2, regardless of clinical symptoms, should be considered for medical observation, home isolation, and further examination.
T174 610-716 Sentence denotes Similarly, patients with symptoms without a known history of exposure should undergo further examinations.
T175 717-808 Sentence denotes The numbers of patients infected with SARS-CoV-2 is rapidly increasing nationwide in China.
T176 809-1023 Sentence denotes Chest CT can detect lung abnormalities with high sensitivity, which is quite helpful for early diagnosis of the disease that can trigger early treatment, which facilitates the containment of this emergency disease.
T177 1024-1194 Sentence denotes Our study showed some common CT imaging features in patients affected by SARS-CoV-2 pneumonia: bilateral, multifocal ground glass opacities, with peripheral distribution.
T178 1195-1312 Sentence denotes Of note, more than half of the patients had multilobar involvement and lesions were more frequent in the lower lobes.
T179 1313-1464 Sentence denotes Pleural effusion, pericardial effusion, cavitation, thoracic lymphadenopathy, and pulmonary emphysema were uncommon imaging findings in these patients.
T180 1465-1557 Sentence denotes Imaging features of viruses’ infections usually appear as multifocal ground glass opacities.
T181 1558-1683 Sentence denotes A previous study identified that ground glass opacities on CT images correspond to pathological diffuse alveolar damage [11].
T182 1684-1793 Sentence denotes Histologically, the opacity of ground glass may be caused by alveoli filled with blood, pus, water, or cells.
T183 1794-1893 Sentence denotes The CT imaging features of viral pneumonia are associated with the pathogenesis of viral infection.
T184 1894-2023 Sentence denotes Most viral pneumonia shares similar imaging features in the same Viridae family because of similarities in the pathogenesis [12].
T185 2024-2171 Sentence denotes SARS-CoV-2 belongs to the family Coronaviridae, so, as expected, the imaging features of SARS-CoV-2 are similar to SARS-CoV and MERS-CoV infection.
T186 2172-2296 Sentence denotes Nonetheless, unilateral involvement is more common than multifocal involvement in the early phase of SARS and MERS [13, 14].
T187 2297-2452 Sentence denotes In our study, the majority of patients showed multifocal involvement in the initial chest CT scan, and this finding is consistent with a recent report [8].
T188 2453-2619 Sentence denotes However, whether this finding is a characteristic feature of the SARS-CoV-2 distinguished from the other two coronaviruses remains to be confirmed by further studies.
T189 2620-2779 Sentence denotes The follow-up CT examination in 52 patients showed that 3 patients who had negative baseline scan, rapidly progressed to with bilateral ground glass opacities.
T190 2780-2942 Sentence denotes Since there is an incubation period after infection with the SARS-CoV-2 [15], a patient may not present any symptoms and imaging abnormalities during this period.
T191 2943-3037 Sentence denotes At present, real-time PCR is used to confirm SARS-CoV-2 infection from respiratory secretions.
T192 3038-3172 Sentence denotes In our study, few patients initially negative for SARS-CoV-2 nucleic acid test had bilateral ground glass opacities in chest CT scans.
T193 3173-3272 Sentence denotes After a few days, patients converted to positive for SARS-CoV-2 nucleic acid test by real-time PCR.
T194 3273-3443 Sentence denotes This points out that patient’s history, clinical manifestations, imaging characteristics, and laboratory tests are all important elements in the diagnosis of the disease.
T195 3444-3475 Sentence denotes Our study had some limitations.
T196 3476-3632 Sentence denotes First of all, we cannot demonstrate any prognostic role for chest CT, because we did not find any correlation between imaging and the course of the disease.
T197 3633-3713 Sentence denotes Also, 52 patients with short-term follow-up chest CT showed disease progression.
T198 3714-3949 Sentence denotes The imaging evaluation of disease progression is not complete, and we will collect more follow-up CT data to observe the evolution and outcome of the disease and provide more imaging information to be correlated with clinical findings.