PMC:7076992 / 54-2072 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T2 0-31 Sentence denotes Challenges in treating COVID-19
T3 32-239 Sentence denotes Coronavirus disease (COVID-19), which appeared in December 2019, presents a global challenge, particularly in the rapid increase of critically ill patients with pneumonia and absence of definitive treatment.
T4 240-310 Sentence denotes To date, over 81,000 cases have been confirmed, with over 2700 deaths.
T5 311-495 Sentence denotes The mortality appears to be around 2%; early published data indicate 25.9% with SARS-CoV-2 pneumonia required ICU admission and 20.1% developed acute respiratory distress syndrome [1].
T6 496-599 Sentence denotes There is presently no vaccine or specific anti-viral drug regime used to treat critically ill patients.
T7 600-732 Sentence denotes The management of patients mainly focuses on the provision of supportive care, e.g., oxygenation, ventilation, and fluid management.
T8 733-916 Sentence denotes Combination treatment of low-dose systematic corticosteroids and anti-virals and atomization inhalation of interferon have been encouraged as part of critical COVID-19 management [2].
T9 917-1036 Sentence denotes Other reported therapeutic agents that are used for the treatment of seriously ill patients have been noted in Table 1.
T10 1037-1084 Sentence denotes Table 1 Potential treatment options of COVID-19
T11 1085-1130 Sentence denotes Classes Potential treatment options Reference
T12 1131-1341 Sentence denotes Anti-viral > 85% of patients received anti-viral agents, including oseltamivir (75 mg every 12 h orally), ganciclovir (0.25 g every 12 h intravenously), and lopinavir/ritonavir tablets (400/100 mg twice daily).
T13 1342-1469 Sentence denotes Remdesivir is currently under trials at more than ten medical institutions in Wuhan and has been known to prevent MERS-CoV. [1]
T14 1470-1651 Sentence denotes Anti-malarial An old anti-malarial, chloroquine phosphate, has been effective in inhibiting the exacerbation of pneumonia due to its anti-viral and anti-inflammatory activities. [3]
T15 1652-1801 Sentence denotes Herbal treatments There was widespread use of Traditional Chinese Medicine during the last SARS-COV outbreak and it is currently being used in China.
T16 1802-2018 Sentence denotes The five most commonly used herbs were Astragali Radix (Huangqi), Glycyrrhizae Radix Et Rhizoma (Gancao), Saposhnikoviae Radix (Fangfeng), Atractylodis Macrocephalae Rhizoma (Baizhu), and Lonicerae Japonicae Flo. [4]