| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T29 |
0-23 |
Sentence |
denotes |
Host-Directed Therapies |
| T30 |
24-399 |
Sentence |
denotes |
Host-directed therapies basically target improvement of the status of the host, improvement of host immune response, or handling of host-related factors associated with viral replication.[6] Apart from immunomodulators, metformin, atorvastatin, fibrates, as well as nutritional supplements may help in treating acute respiratory distress syndrome (ARDS) by boosting immunity. |
| T31 |
400-477 |
Sentence |
denotes |
However, evidence of efficacy in SARS-CoV or MERS-CoV is poorly reported.[24] |
| T32 |
478-813 |
Sentence |
denotes |
Zinc is reported to have antiviral effect,[24] and it inhibits CoV RNA polymerase activity and thus hampers replication in cell culture experiments.[25] As cytokine storm is a pathognomonic feature of COVID-19, inhibition of these pro-inflammatory cytokines may theoretically prove useful (e.g., inhibition of IL-6 by tocilizumab).[24] |
