| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T86 |
0-180 |
Sentence |
denotes |
Being an adenosine analog, remdesivir gets incorporated into viral RNA and causes premature chain termination.[34] The importance of chloroquine as an antiviral agent is coming up. |
| T87 |
181-364 |
Sentence |
denotes |
Chloroquine even showed efficacy as a potent antiviral against SARS-CoV infection and spread.[35] Pretreatment with chloroquine renders vero E6 cells refractory to SARS CoV infection. |
| T88 |
365-582 |
Sentence |
denotes |
Moreover, in the postinfection period, treatment with chloroquine prevents the spread of SARS-CoV infection.[35] Chloroquine increases endosomal pH and thus makes the environment unfavorable for the virus/cell fusion. |
| T89 |
583-871 |
Sentence |
denotes |
Chloroquine also affects the glycosylation process of angiotensin-converting enzyme 2 (ACE-2, receptor for binding of viral spike protein, which is essential for interaction with the host).[35] Being nonexpensive and easily available agent, chloroquine may prove as a promising candidate. |
