PMC:7067204 / 23447-25121 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T227 0-116 Sentence denotes As shown in Figure 7(A–C), the SARS-CoV 5′-UTR contains SL1, SL2, SL3, SL4, S5, SL5A, SL5B, SL5C, SL6, SL7, and SL8.
T228 117-155 Sentence denotes The SL3 contains trans–cis motif [27].
T229 156-295 Sentence denotes The SL1, SL2, SL3, SL4, S5, SL5A, SL5B, and SL5C structures were similar among the 2019-nCoV, human SARS-CoV and the bat SARS-related ZC45.
T230 296-405 Sentence denotes In the 2019-nCoV, part of the S5 found was inside the orf1a/b (marked in red), which was similar to SARS-CoV.
T231 406-472 Sentence denotes In bat SARS-related CoV ZC45, the S5 was not found inside orf1a/b.
T232 473-559 Sentence denotes The 2019-nCoV had the same SL6, SL7, and SL8 as SARS-CoV, and an additional stem loop.
T233 560-631 Sentence denotes Bat SARS-related CoV ZC45 did not have the SARS-COV SL6-like stem loop.
T234 632-690 Sentence denotes Instead, it possessed two other stem loops in this region.
T235 691-733 Sentence denotes All three strains had similar SL7 and SL8.
T236 734-814 Sentence denotes The bat SARS-like CoV ZC45 also had an additional stem loop between SL7 and SL8.
T237 815-921 Sentence denotes Overall, the 5′-UTR of 2019-nCoV was more similar to that of SARS-CoV than the bat SARS-related CoV ZC 45.
T238 922-1028 Sentence denotes The biological relevance and effects of virulence of the 5′-UTR structures should be investigated further.
T239 1029-1141 Sentence denotes The 2019-nCoV had various 3′-UTR structures, including BSL, S1, S2, S3, S4, L1, L2, L3, and HVR (Figure 7(D–F)).
T240 1142-1226 Sentence denotes The 3′-UTR was conserved among 2019-nCoV, human SARS-CoV and SARS-related CoVs [27].
T241 1227-1236 Sentence denotes Figure 7.
T242 1237-1444 Sentence denotes Secondary structure prediction and comparison in the 5′-untranslated region (UTR) and 3′-UTR using the RNAfold WebServer (with minimum free energy and partition function in Fold algorithms and basic options.
T243 1445-1674 Sentence denotes The SARS 5′- and 3′- UTR was used as a reference to adjust the prediction results.(A) SARS-CoV 5'-UTR; (B) 2019-nCoV (HKU-SZ-005b) 5'-UTR; (C) ZC45 5'-UTR; (D) SARS-CoV 3'-UTR; (E) 2019-nCoV (HKU-SZ-005b) 3'-UTR; (F) ZC45 3'-UTR.