| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T19 |
0-153 |
Sentence |
denotes |
The mouse-adapted SARS virus (MA15) [9] was generated by serial passage of an infectious wildtype SARS CoV clone in the respiratory tract of BALB/c mice. |
| T20 |
154-339 |
Sentence |
denotes |
After 15 passages in mice, the SARS-CoV gained elevated replication and lung pathogenesis in aged mice (hence M15), due to six coding genetic mutations associated with mouse adaptation. |
| T21 |
340-452 |
Sentence |
denotes |
It is likely that MA15 is highly attenuated to replicate in human cells or patients due to the mouse adaptation. |
