LitCovid-sentences  

PMC:7048229 / 6092-10181 JSONTXT 9 Projects

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Id Subject Object Predicate Lexical cue
T64 0-7 Sentence denotes Results
T65 8-134 Sentence denotes In the first investigation, we aimed to test whether viral positive can be found in anal swab and blood as well as oral swabs.
T66 135-285 Sentence denotes We conducted a molecular investigation to patients in Wuhan pulmonary hospital, who were detected as oral swabs positive for 2019-nCoV upon admission.
T67 286-396 Sentence denotes We collected blood, oral swabs and anal swabs for 2019-nCoV qPCR test using previously established method [5].
T68 397-477 Sentence denotes We found 15 patients who still carry virus following days of medical treatments.
T69 478-621 Sentence denotes Of these patients, 8 were oral swabs positive (53.3%), 4 were anal swabs positive (26.7%), 6 blood positives (40%) and 3 serum positives (20%).
T70 622-737 Sentence denotes Two patients were positive by both oral swab and anal swab, yet none of the blood positive was also swabs positive.
T71 738-817 Sentence denotes Not surprisingly, all serum positives were also whole serum positive (Table 1).
T72 818-926 Sentence denotes In summary, viral nucleotide can be found in anal swab or blood even if it cannot be detected in oral swabs.
T73 927-1018 Sentence denotes It should be noted that although swabs may be negative, the patient might still be viremic.
T74 1019-1027 Sentence denotes Table 1.
T75 1028-1080 Sentence denotes Molecular detection of 2019-nCoV in swabs and blood.
T76 1081-1142 Sentence denotes Samples were from oral swabs (OS), anal swabs (AS) and blood.
T77 1143-1177 Sentence denotes Data were shown as qPCR Ct values.
T78 1178-1239 Sentence denotes Patients in severe condition during investigation were shown.
T79 1240-1280 Sentence denotes   OS AS Whole blood Serum Severe disease
T80 1281-1304 Sentence denotes Patient 1 33.5       No
T81 1305-1332 Sentence denotes Patient 2     30.3 24.3 Yes
T82 1333-1356 Sentence denotes Patient 3 30.3       No
T83 1357-1380 Sentence denotes Patient 4     32.1   No
T84 1381-1404 Sentence denotes Patient 5   33.1     No
T85 1405-1428 Sentence denotes Patient 6     30.6   No
T86 1429-1455 Sentence denotes Patient 7 32.7 30.2     No
T87 1456-1479 Sentence denotes Patient 8   33.1     No
T88 1480-1506 Sentence denotes Patient 9     31.4 34.5 No
T89 1507-1535 Sentence denotes Patient 10     30.9 33.0 Yes
T90 1536-1560 Sentence denotes Patient 11 27.3       No
T91 1561-1586 Sentence denotes Patient 12 34.4       Yes
T92 1587-1614 Sentence denotes Patient 13 32.9 33.6     No
T93 1615-1639 Sentence denotes Patient 14 32.3       No
T94 1640-1664 Sentence denotes Patient 15     31.6   No
T95 1665-1833 Sentence denotes We then did another investigation to find out the dynamic changes of viral presence in two consecutive studies in both oral and anal swabs in another group of patients.
T96 1834-1930 Sentence denotes The target patients were those who received around 10 days of medical treatments upon admission.
T97 1931-2030 Sentence denotes We tested for both viral antibody and viral nucleotide levels by previously established method [5].
T98 2031-2143 Sentence denotes We showed that both IgM and IgG titres were relatively low or undetectable in day 0 (the day of first sampling).
T99 2144-2347 Sentence denotes On day 5, an increase of viral antibodies can be seen in nearly all patients, which was normally considered as a transition from earlier to later period of infection (Figure 1 and supplementary table 1).
T100 2348-2477 Sentence denotes IgM positive rate increased from 50% (8/16) to 81% (13/16), whereas IgG positive rate increased from 81% (13/16) to 100% (16/16).
T101 2478-2570 Sentence denotes This is in contrast to a relatively low detection positive rate from molecular test (below).
T102 2571-2580 Sentence denotes Figure 1.
T103 2581-2616 Sentence denotes Serological detection of 2019-nCoV.
T104 2617-2704 Sentence denotes Dashed line indicates cutoff, which was determined based on data from healthy controls.
T105 2705-2818 Sentence denotes For molecular detection, we found 8 oral swabs positive (50%) and 4 anal swabs (25%) in these 16 people on day 0.
T106 2819-2883 Sentence denotes On day 5, we were only able to find 4 oral swabs positive (25%).
T107 2884-2936 Sentence denotes In contrast, we found 6 anal swabs positive (37.5%).
T108 2937-3052 Sentence denotes When counting all swab positives together, we found most of the positives came from oral swab (8/10, 80%) on day 0.
T109 3053-3100 Sentence denotes However, this trend appears to change on day 5.
T110 3101-3180 Sentence denotes We found more (6/8, 75%) anal swab positive than oral swab positive (4/8, 50%).
T111 3181-3280 Sentence denotes Another observation is the reoccurrence of virus in 6 patients who were detected negative on day 0.
T112 3281-3350 Sentence denotes Of note, 4 of these 6 viral positives were from anal swabs (Table 2).
T113 3351-3513 Sentence denotes These data suggested a shift from more oral positive during early period (as indicated by antibody titres) to more anal positive during later period might happen.
T114 3514-3522 Sentence denotes Table 2.
T115 3523-3589 Sentence denotes Molecular detection of 2019-nCoV in swabs from two investigations.
T116 3590-3651 Sentence denotes Samples were from oral swabs (OS), anal swabs (AS) and blood.
T117 3652-3686 Sentence denotes Data were shown as qPCR Ct values.
T118 3687-3728 Sentence denotes   Date 0-OS Date 0-AS Date 5-OS Date 5-AS
T119 3729-3749 Sentence denotes Patient 1     23.2  
T120 3750-3770 Sentence denotes Patient 2 30.3      
T121 3771-3791 Sentence denotes Patient 3   19.5    
T122 3792-3815 Sentence denotes Patient 4 32.7 30.2    
T123 3816-3836 Sentence denotes Patient 5   33.1    
T124 3837-3863 Sentence denotes Patient 6 31.1   30.0 31.4
T125 3864-3884 Sentence denotes Patient 7 27.3      
T126 3885-3905 Sentence denotes Patient 8     27.0  
T127 3906-3929 Sentence denotes Patient 9 32.9 33.6    
T128 3930-3951 Sentence denotes Patient 10       23.8
T129 3952-3973 Sentence denotes Patient 11 31.9      
T130 3974-3995 Sentence denotes Patient 12 32.3      
T131 3996-4017 Sentence denotes Patient 13       17.8
T132 4018-4039 Sentence denotes Patient 14       25.5
T133 4040-4061 Sentence denotes Patient 15       30.0
T134 4062-4089 Sentence denotes Patient 16 33.8   26.9 27.5