LitCovid-sentences  

PMC:7039714 / 595-6939 JSONTXT 14 Projects

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Id Subject Object Predicate Lexical cue
T7 0-12 Sentence denotes INTRODUCTION
T8 13-134 Sentence denotes Since December 2019, a succession of cases of pneumonia with unknown causes has appeared in Wuhan, Hubei Province, China.
T9 135-324 Sentence denotes On January 7, 2020, the 2019 novel coronavirus (2019-nCoV or officially named by the World Health Organization as COVID-19) was identified as the causative agent based on virus typing (12).
T10 325-388 Sentence denotes By January 27, 2020, 2823 cases were confirmed, with 81 deaths.
T11 389-505 Sentence denotes To date, there have been a few reports of chest computed tomography (CT) findings in patients infected by 2019-nCoV.
T12 506-631 Sentence denotes Here, we report chest CT findings in two patients confirmed with 2019-nCoV pneumonia at Jiangxi Provincial People's Hospital.
T13 632-777 Sentence denotes This report was approved by Jiangxi Provincial People's Hospital Institutional Review Board, and the requirement for informed consent was waived.
T14 779-790 Sentence denotes CASE REPORT
T15 792-798 Sentence denotes Case 1
T16 799-955 Sentence denotes A 35-year-old man presented with fever for 3 days and cough for 2 days and was admitted to the emergency department of Jiangxi Provincial People's Hospital.
T17 956-1107 Sentence denotes The patient had a history of good physical health with no underlying diseases but had returned to Nanchang, Jiangxi Province, from Wuhan 1 week before.
T18 1108-1397 Sentence denotes Physical examination showed fever, with a body temperature of 38.7℃, and the laboratory examination results showed a normal leukocyte count (5520/µL), increased neutrophils (76.2%), decreased lymphocytes (16.1%), elevated glucose (7.4 mmol/L), and elevated C-reactive protein (14.00 mg/L).
T19 1398-1706 Sentence denotes The patient tested negative for eight common respiratory pathogens, which were respiratory syncytial virus, adenovirus, influenza A virus, Mycoplasma pneumoniae, Chlamydia pneumoniae, Legionella pneumophila, parainfluenza virus, and influenza B virus, and the influenza A antigen screening was also negative.
T20 1707-1881 Sentence denotes Finally, he was diagnosed with 2019-nCoV based on the real-time reverse-transcriptase-polymerase chain reaction (rRT-PCR) amplification of the viral DNA from a sputum sample.
T21 1882-1997 Sentence denotes CT showed multiple regions of patchy consolidation and ground-glass opacities with indistinct border in both lungs.
T22 1998-2102 Sentence denotes The lesions were distributed along the bronchial bundles or within the subpleural lung regions (Fig. 1).
T23 2103-2158 Sentence denotes Neither pleural effusion nor lymphadenopathy was found.
T24 2160-2166 Sentence denotes Case 2
T25 2167-2306 Sentence denotes A 39-year-old man presenting with fever and throat discomfort for 2 days was admitted to Jiangxi Provincial People's Hospital fever clinic.
T26 2307-2375 Sentence denotes He had a history of good physical health and no underlying diseases.
T27 2376-2494 Sentence denotes Although the patient had not visited Wuhan recently, he had a history of contact with the patient described in Case 1.
T28 2495-2805 Sentence denotes Physical examination showed fever, with a temperature of 39.3℃, and laboratory examination results demonstrated a normal leukocyte count (5320/µL), normal neutrophils (67.6%), normal lymphocytes (24.5%), decreased aspartate aminotransferase (14 IU/L), elevated glucose (6.8 mmol/L), and normal CRP (4.00 mg/L).
T29 2806-2896 Sentence denotes Finally, he was diagnosed with 2019-nCoV based on the rRT-PCR analysis of a sputum sample.
T30 2897-2981 Sentence denotes CT imaging showed small ill-defined ground-glass opacities in both lower lung lobes.
T31 2982-3134 Sentence denotes The lesion in the left lower lobe was located in the subpleural region while the one in the right lower lobe was distributed along the bundles (Fig. 2).
T32 3135-3190 Sentence denotes Neither pleural effusion nor lymphadenopathy was found.
T33 3192-3202 Sentence denotes DISCUSSION
T34 3203-3274 Sentence denotes Cases of 2019-nCoV pneumonia are caused by a novel type of coronavirus.
T35 3275-3464 Sentence denotes The 2019-nCoV is the seventh member of the coronavirus family that includes Middle East Respiratory Syndrome Coronavirus and Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) (1234).
T36 3465-3554 Sentence denotes Most early patients had a history of exposure to the South China Seafood Market in Wuhan.
T37 3555-3681 Sentence denotes The source of infection is thought to be wild animals, possibly the Chinese rufous horseshoe bat (Rhinolophus sinicus) (5678).
T38 3682-3763 Sentence denotes Transmission of 2019-nCoV is mainly via droplets but can also be through contact.
T39 3764-3911 Sentence denotes People are generally susceptible to the 2019-nCoV infection and the elderly patients or those with underlying diseases are more seriously affected.
T40 3912-4053 Sentence denotes The incubation period of 2019-nCoV is generally 3–7 days but no longer than 14 days, and the virus is infective during the incubation period.
T41 4054-4105 Sentence denotes The main symptom is fever with a temperature > 38℃.
T42 4106-4235 Sentence denotes Other symptoms include fatigue, dry cough, and diarrhea, and acute respiratory distress syndrome can occur in severe cases (910).
T43 4236-4344 Sentence denotes The two patients described here were admitted to our hospital because of fever and relatively mild symptoms.
T44 4345-4436 Sentence denotes According to the laboratory examination results, both patients had normal leukocyte counts.
T45 4437-4551 Sentence denotes However, case 1 had a reduced percentage of lymphocytes and elevated CRP levels, consistent with viral infections.
T46 4552-4703 Sentence denotes In case 2, the percentage of lymphocytes and CRP levels were normal, although this difference may be attributed to the milder symptoms of this patient.
T47 4704-4767 Sentence denotes As a result, this case was prone to misdiagnosis in the clinic.
T48 4768-4945 Sentence denotes However, 2019-nCoV pneumonia was diagnosed in case 2 based on the characteristic CT findings, which were further confirmed using positive results of the timely rRT-PCR analysis.
T49 4946-5187 Sentence denotes Both patients reported here showed multiple areas of patchy consolidation and ground-glass opacities in both lungs, with most of the lesions distributed along the bronchial bundles or in the subpleural areas, particularly in the lower lobes.
T50 5188-5247 Sentence denotes Neither patient showed pleural effusion or lymphadenopathy.
T51 5248-5469 Sentence denotes In the SARS outbreak in 2003, infected patients exhibited rapid progression of lung lesions, with both lungs showing diffuse infiltration within a short period and producing “white lungs” and mediastinal emphysema (1112).
T52 5470-5600 Sentence denotes In contrast, these lung lesions are relatively mild and are easily misdiagnosed as bronchopneumonia or any common viral infection.
T53 5601-5832 Sentence denotes In addition, no obvious fibrosis was found in these cases, which may be related to the short course and mild intensity of the disease in these patients; this speculation remains to be confirmed using subsequent large-scale studies.
T54 5833-5915 Sentence denotes In conclusion, we report the CT findings in two patients with 2019-nCoV pneumonia.
T55 5916-6000 Sentence denotes Chest CT showed multiple regions of patchy consolidation and ground-glass opacities.
T56 6001-6117 Sentence denotes Furthermore, the lesions were typically distributed along the bronchial bundles or subpleural regions in both lungs.
T57 6118-6344 Sentence denotes In patients with a history of fever or contact with the epidemic area combined with the CT findings described here, timely detection of the novel coronavirus DNA is required to ensure early diagnosis, isolation, and treatment.