PMC:7036342 / 6170-7125 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T33 0-77 Sentence denotes Next-generation sequencing of BetaCoV/Korea/SNU01/2020 (GenBank accession no.
T34 78-182 Sentence denotes MT039890) revealed 9 mutations compared to the NC_045512 reference genome isolated from Wuhan (Table 1).
T35 183-291 Sentence denotes Most of the mutations in our isolate consisted of 70% alternative genes and 30% reference genes (NC_045512).
T36 292-400 Sentence denotes Five variants were found in ORF1ab, one variant in S gene, two variants in ORF3a, and one variant in E gene.
T37 401-463 Sentence denotes Of the nine mutations, six also showed changes in amino acids.
T38 464-655 Sentence denotes When comparing our isolate with the one isolated from the Korea Centers for Disease Control and Prevention (BetaCoV/Korea/KCDC03/2020), 12 variants including the above 9 mutations were found.
T39 656-841 Sentence denotes These mutations may occur by cell culture-adaptation in that our culture isolate was obtained after first blind passage, or by micro-evolution of SARS-CoV-2 before acquisition in Wuhan.
T40 842-955 Sentence denotes Because those genome sequences are quite homologous each other, it is difficult to validate these two hypothesis.