Id |
Subject |
Object |
Predicate |
Lexical cue |
T163 |
0-100 |
Sentence |
denotes |
The genomes of the 2019-nCoV were further analysed to determine its origin and evolutionary history. |
T164 |
101-211 |
Sentence |
denotes |
Full genome comparisons indicated that 2019-nCoV is close to CoVs circulating in Rhinolophus (Horseshoe bats). |
T165 |
212-538 |
Sentence |
denotes |
For example, it shared 98.7% nucleotide identity to bat coronavirus strain BtCoV/4991 (GenBank KP876546, only 370 nt sequence of RdRp gene) and 87.9% nucleotide identity to bat CoV strain bat-SL-CoVZC45 and bat-SL-CoVZXC21, indicating that it was quite divergent from the currently known human CoV, including SARS-CoV (79.7%). |
T166 |
539-710 |
Sentence |
denotes |
To put 2019-nCoV in the context of whole Coronaviridae family, we aligned ORF1b protein sequences from representative CoVs diversity for phylogenetic analyses (Figure 3A). |
T167 |
711-923 |
Sentence |
denotes |
It revealed that the 2019-nCoV is grouped under genus β-coronavirus, subgenus Sarbecovirus, and a cluster that is known to harbour bat-SL-CoVs, many of which were associated with Rhinolophus sp. (horseshoe bats). |
T168 |
924-933 |
Sentence |
denotes |
Figure 3. |
T169 |
934-991 |
Sentence |
denotes |
Origin and evolutionary history of newly identified CoVs. |
T170 |
992-1058 |
Sentence |
denotes |
A. the position of 2019-nCoV in the context of all reference CoVs. |
T171 |
1059-1121 |
Sentence |
denotes |
The phylogeny is constructed based on ORF1b protein alignment. |
T172 |
1122-1186 |
Sentence |
denotes |
For clarity, names were only shown for human-associated viruses. |
T173 |
1187-1286 |
Sentence |
denotes |
Bat associated diversity is shaded with blue and green boxes for alpha- and beta-CoVs respectively. |
T174 |
1287-1451 |
Sentence |
denotes |
B. genome structure of newly identified viruses and its sequence similarity against bat-SL-CoVZC45 and SARS-CoV in a 1000bp sliding window across the entire genome. |
T175 |
1452-1513 |
Sentence |
denotes |
Recombination breakpoints are shown as dashed vertical lines. |
T176 |
1514-1579 |
Sentence |
denotes |
C. the relationship of WHU viruses with the other SARS-like CoVs. |
T177 |
1580-1679 |
Sentence |
denotes |
Phylogeny is reconstructed based on the nucleotide sequence of four genes: namely 1a, 1b, S, and N. |
T178 |
1680-1788 |
Sentence |
denotes |
Those grouped with WHU at S gene are marked red, and those grouped with SARS CoVs at S gene are marked blue. |