PMC:7033698 / 1797-2860 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T18 0-168 Sentence denotes Lack of the definite origin of 2019-nCoV has led to speculation that 2019-nCoV might be derived from genetic manipulation or even for the purpose of use as a bioweapon.
T19 169-218 Sentence denotes This notion has been fully debunked in the media.
T20 219-437 Sentence denotes A recent informally presented report, however, showed that 2019-nCoV had four insertions in the spike glycoprotein gene that is critical for the virus to enter the target cells when compared to other coronaviruses [8].
T21 438-709 Sentence denotes It was claimed that these inserts were either identical or similar to the motifs in the highly variable (V) regions (V1, V4 and V5) in the envelope glycoprotein or in the Gag protein of some unique HIV-1 strains from three different countries (Thailand, Kenya and India).
T22 710-961 Sentence denotes Together with the structure modelling analysis, the authors speculated that these motif insertions sharing similarity with HIV-1 proteins could provide an enhanced affinity towards host cell receptors and increase the range of host cells of 2019-nCoV.
T23 962-1063 Sentence denotes This study implies that 2019-nCoV might be generated by gaining gene fragments from the HIV-1 genome.