PMC:7029449 / 1250-5451 JSONTXT 12 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T7 0-21 Sentence denotes Transmission dynamics
T8 22-234 Sentence denotes Infections with 2019-nCoV can spread from person to person, and in the earliest phase of the outbreak the basic reproductive number was estimated to be around 2.2, assuming a mean serial interval of 7.5 days [2].
T9 235-401 Sentence denotes The serial interval was not precisely estimated, and a potentially shorter mean serial interval would have corresponded to a slightly lower basic reproductive number.
T10 402-526 Sentence denotes Control measures and changes in population behaviour later in January should have reduced the effective reproductive number.
T11 527-768 Sentence denotes However, it is too early to estimate whether the effective reproductive number has been reduced to below the critical threshold of 1 because cases currently being detected and reported would have mostly been infected in mid- to late-January.
T12 769-1004 Sentence denotes Average delays between infection and illness onset have been estimated at around 5–6 days, with an upper limit of around 11-14 days [2,5], and delays from illness onset to laboratory confirmation added a further 10 days on average [2].
T13 1005-1102 Sentence denotes Chains of transmission have now been reported in a number of locations outside of mainland China.
T14 1103-1286 Sentence denotes Within the coming days or weeks it will become clear whether sustained local transmission has been occurring in other cities outside of Hubei province in China, or in other countries.
T15 1287-1552 Sentence denotes If sustained transmission does occur in other locations, it would be valuable to determine whether there is variation in transmissibility by location, for example because of different behaviours or control measures, or because of different environmental conditions.
T16 1553-1738 Sentence denotes To address the latter, virus survival studies can be done in the laboratory to confirm whether there are preferred ranges of temperature or humidity for 2019-nCoV transmission to occur.
T17 1739-1964 Sentence denotes In an analysis of the first 425 confirmed cases of infection, 73% of cases with illness onset between 12 and 22 January reported no exposure to either a wet market or another person with symptoms of a respiratory illness [2].
T18 1965-2175 Sentence denotes The lack of reported exposure to another ill person could be attributed to lack of awareness or recall bias, but China’s health minister publicly warned that pre-symptomatic transmission could be occurring [6].
T19 2176-2379 Sentence denotes Determining the extent to which asymptomatic or pre-symptomatic transmission might be occurring is an urgent priority, because it has direct implications for public health and hospital infection control.
T20 2380-2463 Sentence denotes Data on viral shedding dynamics could help in assessing duration of infectiousness.
T21 2464-2659 Sentence denotes For severe acute respiratory syndrome-related coronavirus (SARS-CoV), infectivity peaked at around 10 days after illness onset [7], consistent with the peak in viral load at around that time [8].
T22 2660-2757 Sentence denotes This allowed control of the SARS epidemic through prompt detection of cases and strict isolation.
T23 2758-2933 Sentence denotes For influenza virus infections, virus shedding is highest on the day of illness onset and relatively higher from shortly before symptom onset until a few days after onset [9].
T24 2934-3093 Sentence denotes To date, transmission patterns of 2019-nCoV appear more similar to influenza, with contagiousness occurring around the time of symptom onset, rather than SARS.
T25 3094-3320 Sentence denotes Transmission of respiratory viruses generally happens through large respiratory droplets, but some respiratory viruses can spread through fine particle aerosols [10], and indirect transmission via fomites can also play a role.
T26 3321-3462 Sentence denotes Coronaviruses can also infect the human gastrointestinal tract [11,12], and faecal-oral transmission might also play a role in this instance.
T27 3463-3722 Sentence denotes The SARS-CoV superspreading event at Amoy Gardens where more than 300 cases were infected was attributed to faecal-oral, then airborne, spread through pressure differentials between contaminated effluent pipes, bathroom floor drains and flushing toilets [13].
T28 3723-4008 Sentence denotes The first large identifiable superspreading event during the present 2019-nCoV outbreak has apparently taken place on the Diamond Princess cruise liner quarantined off the coast of Yokohama, Japan, with at least 130 passengers tested positive for 2019-nCoV as at 10 February 2020 [14].
T29 4009-4201 Sentence denotes Identifying which modes are important for 2019-nCoV transmission would inform the importance of personal protective measures such as face masks (and specifically which types) and hand hygiene.