LitCovid-sentences  

PMC:7029158 / 11671-16229 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T79 0-7 Sentence denotes Results
T80 8-278 Sentence denotes Since Wuhan was locked down on January 23rd, 2020, almost all regions across the country have imposed travel restriction and, at the same time, the case confirmation speed has been improved due to development of new coronavirus nucleic acid-based detection technologies.
T81 279-543 Sentence denotes Under the scenario of adopting the strongest prevention and control strategy and improving the level of detection and treatment in China, the previously estimated basic reproduction number is no longer suitable for evaluating the epidemic trend in the near future.
T82 544-682 Sentence denotes Therefore, we use the updated data to parameterize the proposed model (Tang et al., 2020) and re-estimate the 2019-nCov transmission risk.
T83 683-813 Sentence denotes To estimate the effective daily reproduction ratio, we initially get the time-dependent contact rate c(t) and δI(t) as Fig. 1 (a).
T84 814-962 Sentence denotes Using the discrete values of contact rate c(t) and diagnose rate δI(t), we can calculate the effective daily reproduction ratio, shown in Fig. 1(b).
T85 963-1180 Sentence denotes It follows that under the strict prevention and control measures, the effective daily reproduction ratio Rd(t) has been less than 1 since January 26th, 2020, that is, the number of new infections has begun to decline.
T86 1181-1447 Sentence denotes Note that the effective daily reproduction ratio declined from January 23rd, 2020 to January 25th, 2020, as a combination of the restrictive measures, including the lock-down of Wuhan, contact tracing followed by quarantine and isolation, that have been implemented.
T87 1448-1678 Sentence denotes In practice, this time variation of the contact and diagnose rates leads to sub-exponential rather than exponential growth dynamics, and hence provides better estimates of epidemic size compared to fully exponential growth models.
T88 1679-1822 Sentence denotes We refer to (Pell, Kuang, Viboud, & Chowell, 2018; Smirnova & Chowell, 2017) for earlier studies on sub-exponential growth of modern epidemics.
T89 1823-1995 Sentence denotes Fig. 1 (A) Time-dependent contact rate c(t) and diagnose rate δI(t); (B) Effective daily reproduction ratio Rd(t), declining due to reduction of c(t) and increase of δI(t).
T90 1996-2122 Sentence denotes Near-casting in a rapidly evolving situation requires timely information of the implementation of public health interventions.
T91 2123-2282 Sentence denotes We emphasize that this information is not only about the policy and decision, but also the implementation which is highly dependent on the resources available.
T92 2283-2531 Sentence denotes We illustrate this with two simulated predictions: one based on the assumption that the interventions implemented during January 23rd, 2020 to January 29th, 2020 will be sustained, and another one based on additional data beyond January 29th, 2020.
T93 2532-2762 Sentence denotes We first plot the time series on the predicted number of reported cases, i.e., the number of hospitalized individuals H(t) and the predicted cumulative cases based on the updated parameters listed in Table 1, and shown in Fig. 2 .
T94 2763-3000 Sentence denotes It shows that the number of hospitalized individuals will peak on around February 4th, 2020 (Fig. 2(A, C)), while the predicted number of cumulative cases will continue to grow for some duration but with a slower growth rate (Fig. 2(D)).
T95 3001-3174 Sentence denotes Moreover, sensitivity analysis revealed that further enhanced measures can reduce the peak value and hence decrease the predicted cumulative case numbers ((Fig. 2(A and B)).
T96 3175-3489 Sentence denotes We caution that increasing the number of susceptible individuals may lead to an increase in the peak value and enlarge the predicted cumulative case numbers ((Fig. 2(C and D)), emphasizing the importance of sustaining the implemented control strategies such as self-isolation in order to reduce the susceptibility.
T97 3490-3658 Sentence denotes We emphasize that the peak time is defined here as the time when the number of confirmed cases reaches the maximum, so sustaining the intervention measures is critical.
T98 3659-4030 Sentence denotes Fig. 2 Predictions and effect of control measures on infection based on assumption that parameters obtained from fitting the data from January 23rd to January 29th, 2020 (and hence the interventions) remain unchanged. (A–B) Decreasing the minimum contact rate after January 29th, 2020; (C–D) Decreasing/increasing the susceptible population size as of January 29th, 2020.
T99 4031-4204 Sentence denotes We repeated the procedure as above but fitted our model to the data of confirmed cases between January 23rd and February 1st, 2020 (Fig. 3 ) and observed the improved δI(t).
T100 4205-4338 Sentence denotes As a result, in comparison with the results in Fig. 2, we obtained higher projected cumulative confirmed cases and delayed peak time.
T101 4339-4558 Sentence denotes Fig. 3 Best fitting of the model to the data of cumulative confirmed cases between January 23rd and February 1st, 2020: the projected number of infected (A), quarantined infected (B), and cumulative confirmed cases (C).