Id |
Subject |
Object |
Predicate |
Lexical cue |
T13 |
0-141 |
Sentence |
denotes |
Porcine epidemic diarrhea virus (PEDV) is an enveloped, positive-sense and single stranded RNA virus belonging to the genus Alphacoronavirus. |
T14 |
142-351 |
Sentence |
denotes |
PEDV is the causative agent of porcine epidemic diarrhea (PED), a historic, highly contagious enteric swine disease characterized by diarrhea, dehydration and poor growth performance in pigs at all ages [1,2]. |
T15 |
352-548 |
Sentence |
denotes |
PED was first identified in 1971 in the United Kingdom, and subsequently became an endemic disease in the Europe and most Asian countries with a low mortality rate and limited economic losses [1]. |
T16 |
549-689 |
Sentence |
denotes |
For decades, the disease was controlled through the use of live attenuated vaccines (LAVs) derived from the PEDV prototypes, CV777- or DR13. |
T17 |
690-823 |
Sentence |
denotes |
Unfortunately, in late 2010, a new highly virulent PEDV strain emerged in China and quickly spread worldwide, including Taiwan [3,4]. |
T18 |
824-1084 |
Sentence |
denotes |
Moreover, the conventional LAV failed to induce protection against this new virulent PEDV strain, consequently resulting in nearly 100% mortality amongst neonatal piglets and leading to substantial economic impacts on swine markets in the affected regions [5]. |
T19 |
1085-1148 |
Sentence |
denotes |
Phylogenetic analysis categorizes PEDV into two genogroups [2]. |
T20 |
1149-1346 |
Sentence |
denotes |
Genogroup I consists primarily of the historic, low-virulent PEDV strains that appeared around 1970, whereas genogroup II is composed of the highly virulent PEDV strains, which emerged after 2010s. |
T21 |
1347-1554 |
Sentence |
denotes |
Both genogroups can be further divided into two subgroups each, namely G1a, G1b, G2a and G2b though a recent phylogenetic study identified a novel recombinant PEDV strain classified into a new G1c clade [6]. |