LitCovid-sentences  

PMC:7014668 / 8749-12903 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T60 0-26 Sentence denotes Discussion and conclusions
T61 27-197 Sentence denotes As a response to the ongoing outbreak of the 2019-nCoV originating in Wuhan, exit screening has been implemented for international flights leaving China’s major airports.
T62 198-395 Sentence denotes Thermal scanning, which can identify passengers with fever (high external body temperature), allows for passengers exhibiting symptoms of 2019-nCoV infection to be tested before they board a plane.
T63 396-547 Sentence denotes Similarly, entry screening for flights originating in the most affected regions may be under consideration at airports in regions in and outside China.
T64 548-894 Sentence denotes We estimate that the key goal of syndromic screening at airports - to prevent infected travellers from entering countries or regions with little or no ongoing transmission - is only achievable if the rate of asymptomatic infections that are transmissible is negligible, screening sensitivity is almost perfect, and the incubation period is short.
T65 895-1086 Sentence denotes Based on early data from Li et al. [8], 2019-nCoV appears to have a shorter incubation period than severe acute respiratory syndrome (SARS), and a higher rate of asymptomatic infections [11].
T66 1087-1209 Sentence denotes Under generally conservative assumptions on sensitivity, we find that 46 of 100 infected travellers will enter undetected.
T67 1210-1317 Sentence denotes Entry screening is an intuitive barrier for the prevention of infected people entering a country or region.
T68 1318-1502 Sentence denotes However, evidence on its effectiveness remains limited and given its lack of specificity, it generates a high overhead of screened travellers uninfected with the targeted pathogen [5].
T69 1503-1695 Sentence denotes For example, when entry screening was implemented in Australia in response to the 2003 SARS outbreak, 1.84 million people were screened, 794 were quarantined, and no cases were confirmed [12].
T70 1696-1904 Sentence denotes While some cases of 2019-nCoV infection have been identified through airport screening in the current outbreak, our estimates indicate that likely more infected travellers have not been detected by screening.
T71 1905-2074 Sentence denotes It is important to note that our estimates are based on a number of key assumptions that cannot yet be informed directly by evidence from the ongoing 2019-nCoV outbreak.
T72 2075-2204 Sentence denotes The current outbreak has spread rapidly and early evidence suggests that the average disease severity is lower than that of SARS.
T73 2205-2274 Sentence denotes This may also suggest a substantial proportion of asymptomatic cases.
T74 2275-2479 Sentence denotes A recent analysis of a family transmission cluster is based on a small sample size but one in six infections was asymptomatic [11]; this is a major impediment for the effectiveness of syndromic screening.
T75 2480-2598 Sentence denotes However, if asymptomatic cases were not infectious they would not pose a risk for seeding infection chains on arrival.
T76 2599-2805 Sentence denotes To allow easy adaptation of our results as new insight becomes available in the coming weeks, we developed a free interactive online tool, available at https://cmmid-lshtm.shinyapps.io/traveller_screening/.
T77 2806-3022 Sentence denotes While the most up-to-date data on the incubation period or the time until recovery from 2019-nCoV infection have been used in this analysis, these figures are likely to change over time as more data become available.
T78 3023-3286 Sentence denotes Unless the incubation period is only a small fraction of the duration of infection in relation to that of symptomatic disease, and fever in particular, syndromic screening is likely to detect an insufficient fraction of infected cases to prevent local infections.
T79 3287-3391 Sentence denotes In addition, the sensitivity of airport screening for the detection of 2019-nCoV has not been evaluated.
T80 3392-3536 Sentence denotes However, we chose conservative estimates and show that with reduced sensitivity, the effectiveness of syndromic screening would further decline.
T81 3537-3702 Sentence denotes In many international airports, information is provided to travellers from affected regions recommending action if they develop symptoms on or after arrival [13-16].
T82 3703-3857 Sentence denotes Some countries, for example Japan, also require incoming passengers to complete forms detailing their past and future travel in order to aid tracing [17].
T83 3858-4154 Sentence denotes Due to the duration of the incubation period of 2019-nCoV infection, we find that exit or entry screening at airports for initial symptoms, via thermal scanners or similar, is unlikely to prevent passage of infected travellers into new countries or regions where they may seed local transmission.