PMC:7001239 / 6259-7765 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T45 0-58 Sentence denotes Transmission characteristics of the 2019 novel coronavirus
T46 59-278 Sentence denotes In order to reach between 1,000 and 9,700 infected cases by 18 January 2020, the early human-to-human transmission of 2019-nCoV was characterised by values of R0 around 2.2 (median value, with 90% high density interval:
T47 279-299 Sentence denotes 1.4–3.8) (Figure 1).
T48 300-415 Sentence denotes The observed data at this point are compatible with a large range of values for the dispersion parameter k (median:
T49 416-448 Sentence denotes 0.54, 90% high density interval:
T50 449-461 Sentence denotes 0.014–6.95).
T51 462-537 Sentence denotes However, our simulations suggest that very low values of k are less likely.
T52 538-701 Sentence denotes These estimates incorporate the uncertainty about the total epidemic size on 18 January 2020 and about the date and scale of the initial zoonotic event (Figure 2).
T53 702-838 Sentence denotes Figure 1 Values of R0 and k most compatible with the estimated size of the 2019 novel coronavirus epidemic in China, on 18 January 2020
T54 839-911 Sentence denotes The basic reproduction number R0 quantifies human-to-human transmission.
T55 912-1058 Sentence denotes The dispersion parameter k quantifies the risk of a superspreading event (lower values of k are linked to a higher probability of superspreading).
T56 1059-1129 Sentence denotes Note that the probability density of k implies a log10 transformation.
T57 1130-1230 Sentence denotes Figure 2 Illustration of the simulation strategy, 2019 novel coronavirus outbreak, China, 2019–2020
T58 1231-1322 Sentence denotes The lines represent the cumulative incidence of 480 simulations with R0 = 1.8 and k = 1.13.
T59 1323-1384 Sentence denotes The other parameters are left to vary according to the Table.
T60 1385-1506 Sentence denotes Among these simulated epidemics, 54.3% led to a cumulative incidence between 1,000 and 9,700 on 18 January 2020 (in red).