Id |
Subject |
Object |
Predicate |
Lexical cue |
T75 |
0-113 |
Sentence |
denotes |
Comparison of two hypothetical scenarios: one with large zoonotic spillover and one with small zoonotic spillover |
T76 |
114-295 |
Sentence |
denotes |
To date, as at 22 January, official information has not been sufficient to determine the source of infection and risk of human-to-human transmission for the newly emerged 2019-nCoV. |
T77 |
296-489 |
Sentence |
denotes |
Two competing hypotheses are therefore proposed and compared as potential explanations for the characteristics of the current outbreak of 2019-nCoV infections within and outside mainland China. |
T78 |
490-675 |
Sentence |
denotes |
Scenario 1 comprises a large zoonotic spillover event starting in early December 2019, perhaps over a number of days or weeks, and very limited human-to-human transmission subsequently. |
T79 |
676-803 |
Sentence |
denotes |
Scenario 2 comprises a small zoonotic spillover event in early December 2019 followed by efficient human-to-human transmission. |
T80 |
804-898 |
Sentence |
denotes |
Evidence consistent or inconsistent with each of these two scenarios is outlined in the Table. |
T81 |
899-997 |
Sentence |
denotes |
Table Evidence on transmission dynamics of human infections with 2019-nCoV, as at 22 January 2020 |
T82 |
998-1077 |
Sentence |
denotes |
Observation Date Interpretation Supports Scenario 1?a Supports Scenario 2?b |
T83 |
1078-1222 |
Sentence |
denotes |
By 20 January, 198 laboratory-confirmed cases, 3 fatal, 25 recovered [28] 20 Jan 2020 Fatality risk among hospitalised cases is 11%c Yes Yes |
T84 |
1223-1438 |
Sentence |
denotes |
No infections among the more than 700 people under medical surveillance, including HCWs [28] 20 Jan 2020 Very low human-to-human transmissibility Yes No (Note: assuming adequate contact tracing and surveillance) |
T85 |
1439-1627 |
Sentence |
denotes |
Only one likely human-to-human cluster among the first 41 cases [18] 20 Jan 2020 Very low human-to-human transmissibility (R 0 of 0.02) Yes No (Note: assuming adequate contact tracing) |
T86 |
1628-1885 |
Sentence |
denotes |
Only approximately 70% of the first 41 cases had exposure to Southern China Seafood Wholesale Market [16] 15 Jan 2020 Low human-to-human transmissibility (R 0 of 0.3) Yes No (Note: possible selection bias towards identifying cases linked to that market) |
T87 |
1886-2096 |
Sentence |
denotes |
New cases with a travel history to Wuhan before onset were confirmed in other cities in China [29] 20 Jan 2020 Indicative of many mild to moderate infections (not requiring hospitalisation) in Wuhan Yes Yes |
T88 |
2097-2321 |
Sentence |
denotes |
Four exported cases to other countries, all with relatively mild illness [30,31] 12–20 Jan 2020 Indicative of many mild to moderate infections not necessitating hospitalisation or outpatient medical care in Wuhan Yes Yes |
T89 |
2322-2524 |
Sentence |
denotes |
Four exported cases, at least three of whom had no contact with Southern China Seafood Wholesale Market [30,31] 12–20 Jan 2020 At least some limited human-to-human transmission (unclear R 0) Yes Yes |
T90 |
2525-2801 |
Sentence |
denotes |
Two family clusters in Guangdong, with family members who did not visit Wuhan but were infected after the other family member(s) returning from Wuhan were confirmed with the infection [29] 20 Jan 2020 At least some limited human-to-human transmission (unclear R 0) Yes Yes |
T91 |
2802-2957 |
Sentence |
denotes |
15 HCWs confirmed with infection of 2019-nCoV (not clear whether infections were from one case or multiple cases) [20] 20 Jan 2020 Super-spreading event? |
T92 |
2958-3072 |
Sentence |
denotes |
Could still be consistent with limited human-to-human transmission if an isolated incident (unclear R 0) Yes Yes |
T93 |
3073-3426 |
Sentence |
denotes |
Exported cases identified in Taiwan and the United States with illness onset dates on 11 and 19 January [32,33] 22 Jan 2020 Could be because of surveillance bias, but is more consistent with an increase in incidence of infections over time No (Note: possible selection bias because of enhanced surveillance towards identifying more recent cases) Yes |
T94 |
3427-3511 |
Sentence |
denotes |
HCWs: healthcare workers; nCoV: novel coronavirus; MHC: Municipal Health Commission. |
T95 |
3512-3594 |
Sentence |
denotes |
a Most infections are zoonotic with limited human-to-human transmission (R 0 < 1). |
T96 |
3595-3677 |
Sentence |
denotes |
b Initial zoonotic spillover with efficient human-to-human transmission (R 0 > 1). |
T97 |
3678-3741 |
Sentence |
denotes |
c Estimated as (fatal cases) / (fatal cases + recovered cases). |