PMC:6988272 / 10463-14204 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T75 0-113 Sentence denotes Comparison of two hypothetical scenarios: one with large zoonotic spillover and one with small zoonotic spillover
T76 114-295 Sentence denotes To date, as at 22 January, official information has not been sufficient to determine the source of infection and risk of human-to-human transmission for the newly emerged 2019-nCoV.
T77 296-489 Sentence denotes Two competing hypotheses are therefore proposed and compared as potential explanations for the characteristics of the current outbreak of 2019-nCoV infections within and outside mainland China.
T78 490-675 Sentence denotes Scenario 1 comprises a large zoonotic spillover event starting in early December 2019, perhaps over a number of days or weeks, and very limited human-to-human transmission subsequently.
T79 676-803 Sentence denotes Scenario 2 comprises a small zoonotic spillover event in early December 2019 followed by efficient human-to-human transmission.
T80 804-898 Sentence denotes Evidence consistent or inconsistent with each of these two scenarios is outlined in the Table.
T81 899-997 Sentence denotes Table Evidence on transmission dynamics of human infections with 2019-nCoV, as at 22 January 2020
T82 998-1077 Sentence denotes Observation Date Interpretation Supports Scenario 1?a Supports Scenario 2?b
T83 1078-1222 Sentence denotes By 20 January, 198 laboratory-confirmed cases, 3 fatal, 25 recovered [28] 20 Jan 2020 Fatality risk among hospitalised cases is 11%c Yes Yes
T84 1223-1438 Sentence denotes No infections among the more than 700 people under medical surveillance, including HCWs [28] 20 Jan 2020 Very low human-to-human transmissibility Yes No (Note: assuming adequate contact tracing and surveillance)
T85 1439-1627 Sentence denotes Only one likely human-to-human cluster among the first 41 cases [18] 20 Jan 2020 Very low human-to-human transmissibility (R 0 of 0.02) Yes No (Note: assuming adequate contact tracing)
T86 1628-1885 Sentence denotes Only approximately 70% of the first 41 cases had exposure to Southern China Seafood Wholesale Market [16] 15 Jan 2020 Low human-to-human transmissibility (R 0 of 0.3) Yes No (Note: possible selection bias towards identifying cases linked to that market)
T87 1886-2096 Sentence denotes New cases with a travel history to Wuhan before onset were confirmed in other cities in China [29] 20 Jan 2020 Indicative of many mild to moderate infections (not requiring hospitalisation) in Wuhan Yes Yes
T88 2097-2321 Sentence denotes Four exported cases to other countries, all with relatively mild illness [30,31] 12–20 Jan 2020 Indicative of many mild to moderate infections not necessitating hospitalisation or outpatient medical care in Wuhan Yes Yes
T89 2322-2524 Sentence denotes Four exported cases, at least three of whom had no contact with Southern China Seafood Wholesale Market [30,31] 12–20 Jan 2020 At least some limited human-to-human transmission (unclear R 0) Yes Yes
T90 2525-2801 Sentence denotes Two family clusters in Guangdong, with family members who did not visit Wuhan but were infected after the other family member(s) returning from Wuhan were confirmed with the infection [29] 20 Jan 2020 At least some limited human-to-human transmission (unclear R 0) Yes Yes
T91 2802-2957 Sentence denotes 15 HCWs confirmed with infection of 2019-nCoV (not clear whether infections were from one case or multiple cases) [20] 20 Jan 2020 Super-spreading event?
T92 2958-3072 Sentence denotes Could still be consistent with limited human-to-human transmission if an isolated incident (unclear R 0) Yes Yes
T93 3073-3426 Sentence denotes Exported cases identified in Taiwan and the United States with illness onset dates on 11 and 19 January [32,33] 22 Jan 2020 Could be because of surveillance bias, but is more consistent with an increase in incidence of infections over time No (Note: possible selection bias because of enhanced surveillance towards identifying more recent cases) Yes
T94 3427-3511 Sentence denotes HCWs: healthcare workers; nCoV: novel coronavirus; MHC: Municipal Health Commission.
T95 3512-3594 Sentence denotes a Most infections are zoonotic with limited human-to-human transmission (R 0 < 1).
T96 3595-3677 Sentence denotes b Initial zoonotic spillover with efficient human-to-human transmission (R 0 > 1).
T97 3678-3741 Sentence denotes c Estimated as (fatal cases) / (fatal cases + recovered cases).