PubMed:32247326 JSONTXT 12 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-141 Sentence denotes Evolving epidemiology and transmission dynamics of coronavirus disease 2019 outside Hubei province, China: a descriptive and modelling study.
TextSentencer_T2 142-153 Sentence denotes BACKGROUND:
TextSentencer_T3 154-364 Sentence denotes The coronavirus disease 2019 (COVID-19) epidemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began in Wuhan city, Hubei province, in December, 2019, and has spread throughout China.
TextSentencer_T4 365-522 Sentence denotes Understanding the evolving epidemiology and transmission dynamics of the outbreak beyond Hubei would provide timely information to guide intervention policy.
TextSentencer_T5 523-531 Sentence denotes METHODS:
TextSentencer_T6 532-709 Sentence denotes We collected individual information from official public sources on laboratory-confirmed cases reported outside Hubei in mainland China for the period of Jan 19 to Feb 17, 2020.
TextSentencer_T7 710-897 Sentence denotes We used the date of the fourth revision of the case definition (Jan 27) to divide the epidemic into two time periods (Dec 24 to Jan 27, and Jan 28 to Feb 17) as the date of symptom onset.
TextSentencer_T8 898-994 Sentence denotes We estimated trends in the demographic characteristics of cases and key time-to-event intervals.
TextSentencer_T9 995-1108 Sentence denotes We used a Bayesian approach to estimate the dynamics of the net reproduction number (Rt) at the provincial level.
TextSentencer_T10 1109-1118 Sentence denotes FINDINGS:
TextSentencer_T11 1119-1169 Sentence denotes We collected data on 8579 cases from 30 provinces.
TextSentencer_T12 1170-1347 Sentence denotes The median age of cases was 44 years (33-56), with an increasing proportion of cases in younger age groups and in elderly people (ie, aged >64 years) as the epidemic progressed.
TextSentencer_T13 1348-1538 Sentence denotes The mean time from symptom onset to hospital admission decreased from 4·4 days (95% CI 0·0-14·0) for the period of Dec 24 to Jan 27, to 2·6 days (0·0-9·0) for the period of Jan 28 to Feb 17.
TextSentencer_T14 1539-1677 Sentence denotes The mean incubation period for the entire period was estimated at 5·2 days (1·8-12·4) and the mean serial interval at 5·1 days (1·3-11·6).
TextSentencer_T15 1678-1828 Sentence denotes The epidemic dynamics in provinces outside Hubei were highly variable but consistently included a mixture of case importations and local transmission.
TextSentencer_T16 1829-2043 Sentence denotes We estimated that the epidemic was self-sustained for less than 3 weeks, with mean Rt reaching peaks between 1·08 (95% CI 0·74-1·54) in Shenzhen city of Guangdong province and 1·71 (1·32-2·17) in Shandong province.
TextSentencer_T17 2044-2188 Sentence denotes In all the locations for which we had sufficient data coverage of Rt, Rt was estimated to be below the epidemic threshold (ie, <1) after Jan 30.
TextSentencer_T18 2189-2204 Sentence denotes INTERPRETATION:
TextSentencer_T19 2205-2378 Sentence denotes Our estimates of the incubation period and serial interval were similar, suggesting an early peak of infectiousness, with possible transmission before the onset of symptoms.
TextSentencer_T20 2379-2550 Sentence denotes Our results also indicate that, as the epidemic progressed, infectious individuals were isolated more quickly, thus shortening the window of transmission in the community.
TextSentencer_T21 2551-2773 Sentence denotes Overall, our findings indicate that strict containment measures, movement restrictions, and increased awareness of the population might have contributed to interrupt local transmission of SARS-CoV-2 outside Hubei province.
TextSentencer_T22 2774-2782 Sentence denotes FUNDING:
TextSentencer_T23 2783-2924 Sentence denotes National Science Fund for Distinguished Young Scholars, National Institute of General Medical Sciences, and European Commission Horizon 2020.