PubMed:32232433 JSONTXT 12 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-113 Sentence denotes Characteristics of Ocular Findings of Patients With Coronavirus Disease 2019 (COVID-19) in Hubei Province, China.
TextSentencer_T2 114-125 Sentence denotes Importance:
TextSentencer_T3 126-394 Sentence denotes While the outbreak of coronavirus disease 2019 (COVID-19) has resulted in more than 100 000 infected individuals in China and worldwide, there are few reports on the association of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with ocular abnormalities.
TextSentencer_T4 395-563 Sentence denotes Understanding ocular manifestations of patients with COVID-19 by ophthalmologists and others may facilitate the diagnosis and prevention of transmission of the disease.
TextSentencer_T5 564-574 Sentence denotes Objective:
TextSentencer_T6 575-678 Sentence denotes To investigate ocular manifestations and viral prevalence in the conjunctiva of patients with COVID-19.
TextSentencer_T7 679-713 Sentence denotes Design, Setting, and Participants:
TextSentencer_T8 714-898 Sentence denotes In this case series, patients with COVID-19 treated from February 9 to 15, 2020, at a hospital center in Hubei province, China, were retrospectively reviewed for ocular manifestations.
TextSentencer_T9 899-1138 Sentence denotes During the period of treatment, the ocular signs and symptoms as well as results of blood tests and reverse transcriptase-polymerase chain reaction (RT-PCR) from nasopharyngeal and conjunctival swabs for SARS-CoV-2 were noted and analyzed.
TextSentencer_T10 1139-1166 Sentence denotes Main Outcomes and Measures:
TextSentencer_T11 1167-1253 Sentence denotes Ocular signs and symptoms as well as results of blood tests and RT-PCR for SARS-CoV-2.
TextSentencer_T12 1254-1262 Sentence denotes Results:
TextSentencer_T13 1263-1393 Sentence denotes Of the 38 included patients with clinically confirmed COVID-19, 25 (65.8%) were male, and the mean (SD) age was 65.8 (16.6) years.
TextSentencer_T14 1394-1629 Sentence denotes Among them, 28 patients (73.7%) had positive findings for COVID-19 on RT-PCR from nasopharyngeal swabs, and of these, 2 patients (5.2%) yielded positive findings for SARS-CoV-2 in their conjunctival as well as nasopharyngeal specimens.
TextSentencer_T15 1630-1822 Sentence denotes A total of 12 of 38 patients (31.6%; 95% CI, 17.5-48.7) had ocular manifestations consistent with conjunctivitis, including conjunctival hyperemia, chemosis, epiphora, or increased secretions.
TextSentencer_T16 1823-2068 Sentence denotes By univariate analysis, patients with ocular symptoms were more likely to have higher white blood cell and neutrophil counts and higher levels of procalcitonin, C-reactive protein, and lactate dehydrogenase than patients without ocular symptoms.
TextSentencer_T17 2069-2225 Sentence denotes In addition, 11 of 12 patients with ocular abnormalities (91.7%; 95% CI, 61.5-99.8) had positive results for SARS-CoV-2 on RT-PCR from nasopharyngeal swabs.
TextSentencer_T18 2226-2340 Sentence denotes Of these, 2 (16.7%) had positive results for SARS-CoV-2 on RT-PCR from both conjunctival and nasopharyngeal swabs.
TextSentencer_T19 2341-2367 Sentence denotes Conclusions and Relevance:
TextSentencer_T20 2368-2509 Sentence denotes In this study, one-third of patients with COVID-19 had ocular abnormalities, which frequently occurred in patients with more severe COVID-19.
TextSentencer_T21 2510-2609 Sentence denotes Although there is a low prevalence of SARS-CoV-2 in tears, it is possible to transmit via the eyes.